Characterization and hypoglycemic activity of a β-pyran polysaccharides from bamboo shoot ( Leleba oldhami Nakal) shells

Zheng, Yafeng; Zhang, Shuai; Wang, Qi; Lu, Xu; Lin, Liangmei; Tian, Yuting; Xiao, Jianbo; Zheng, Baodong

doi:10.1016/j.carbpol.2016.02.073

Cited by 90 publications

(39 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the positive control (PC) group, STZ‐diabetic rats were treated with 400 mg/kg of metformin hydrochloride (Zhang and others , ). In the high‐dose (HD), medium‐dose (MD), and low‐dose (LD) SCP‐80‐I groups, STZ‐diabetic rats were treated with 400, 200, and 100 mg/kg SCP‐80‐I, respectively (Wang and others ; Zheng and others ). Treatments were conveyed into the stomach through the mouth daily.…”

Section: Methodsmentioning

confidence: 99%

Hypoglycemic Activity of Polysaccharides from Sweet Corncob on Streptozotocin‐Induced Diabetic Rats

Yong

Wang

Gao

2016

Journal of Food Science

View full text Add to dashboard Cite

A water-soluble polysaccharide (SCP-80-I) was isolated from sweet corncob using microwave-assisted compound-enzyme extraction and column chromatography. SCP-80-I is composed mainly of arabinose, mannose, glucose, and galactose in a molar ratio of 0.369:0.824:10.759:0.333, and has a molecular mass of 18350 Da and β-glycosides linkages in its molecular structure. The preliminary hypoglycemic and hypolipidemic activity in streptozotocin-induced diabetic rats was investigated. Rats were administered daily with 100, 200, and 400 mg/kg SCP-80-I for 21 d. The SCP-80-I increased the rat body mass significantly and reduced the blood glucose level in a dose-dependent manner. The SCP-80-I reduced liver swelling; kidney and pancreas hypertrophy; and total cholesterol, triglyceride, and low-density lipoprotein-C levels significantly; and increased the level of high-density lipoproteins in streptozotocin-induced diabetic rats. These results indicate that SCP-80-I exerts a potential hypoglycemic effect in streptozotocin-induced diabetic rats.

show abstract

Section: Methodsmentioning

confidence: 99%

Hypoglycemic Activity of Polysaccharides from Sweet Corncob on Streptozotocin‐Induced Diabetic Rats

Yong

Wang

Gao

2016

Journal of Food Science

View full text Add to dashboard Cite

show abstract

“…Recently, therapies directed at other coincident features, such as obesity and IR, have also been a major focus of research and therapy [20]. Food and the functional components rich in phytochemicals, such as polyphenols, polysaccharides, oligosaccharides, and so on, can be very effective antidiabetic agents [15,[21][22][23][24][25].…”

Section: Type 2 Diabetes Mellitusmentioning

confidence: 99%

miRNAs as Regulators of Antidiabetic Effects of Fucoidans

Zhao

Lai

et al. 2019

eFood

Self Cite

View full text Add to dashboard Cite

Diabetes mellitus is a metabolic disease with a high mortality rate worldwide. MicroRNAs (miRNAs), and other small noncoding RNAs, serve as endogenous gene regulators through binding to specific sequences in RNA and modifying gene expression toward up-or down-regulation. miRNAs have become compelling therapeutic targets and play crucial roles in regulating the process of insulin resistance. Fucoidan has shown potential function as an a-amylase inhibitor, which may be beneficial in the management of type 2 diabetes mellitus. In recent years, many studies on fucoidan focused on the decrease in blood glucose levels caused by ingesting low-glucose food or glucose-lowering components. However, the importance of miRNAs as regulators of antidiabetic effects was rarely recognized. Hence, this review emphasizes the antidiabetic mechanisms of fucoidan through regulation of miRNAs. Fucoidan exerts a vital antidiabetic effect by regulation of miRNA expression and thus provides a novel biological target for future research.

show abstract

“…Because of its rich nutritional components, bamboo-shoot shell can be used as a complete medium to culture microorganisms such as A. niger (Jia et al, 2011). Furthermore, the derivatives from components of bamboo-shoot shell can be used as feedstocks for other conversions (Qing et al, 2016;Ye et al, 2015;Zheng et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

A possible water-soluble inducer for synthesis of cellulase in Aspergillus niger

Zhang

Thakur

et al. 2017

Bioresource Technology

View full text Add to dashboard Cite

Characterization and hypoglycemic activity of a β-pyran polysaccharides from bamboo shoot ( Leleba oldhami Nakal) shells

Cited by 90 publications

References 28 publications

Hypoglycemic Activity of Polysaccharides from Sweet Corncob on Streptozotocin‐Induced Diabetic Rats

Hypoglycemic Activity of Polysaccharides from Sweet Corncob on Streptozotocin‐Induced Diabetic Rats

miRNAs as Regulators of Antidiabetic Effects of Fucoidans

A possible water-soluble inducer for synthesis of cellulase in Aspergillus niger

Contact Info

Product

Resources

About