2010
DOI: 10.1177/104063871002200404
|View full text |Cite
|
Sign up to set email alerts
|

Characterization and Phylogenetic Analysis of Bovine Viral Diarrhea Virus in Brain Tissues from Nonambulatory (Downer) Cattle in Korea

Abstract: Abstract. Between August 2008 and May 2009, 386 brain and serum samples from adult cattle (2-7 years old) showing a variety of clinical signs of downer cow syndrome were received by the National Veterinary Research and Quarantine Service. All brain samples were tested for the presence of Bovine viral diarrhea virus (BVDV) by reverse transcription polymerase chain reaction (RT-PCR), immunohistochemistry (IHC), and antigen capture ELISA (Ag-ELISA). The BVDV nucleic acid was detected in 54 of 386 (15.5%) brain sa… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

1
6
0
2

Year Published

2012
2012
2019
2019

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 10 publications
(9 citation statements)
references
References 28 publications
1
6
0
2
Order By: Relevance
“…As shown in Table 4 and reported elsewhere [ 36 ], of the cattle with positive results by to RT-PCR, both Ab-positive and-negative results were detected. The double positive status to both BVDV Ab and nucleic acid detection might indicate an acute infection stage, while that positive to nucleic acid but negative to Ab detection might suggest either an early phase of acute infection, because development of detectable Ab usually requires 1–2 weeks after infection, or a persistent infection in which Ab detection is negative, but positive for both nucleic acid and Ag detection.…”
Section: Discussionsupporting
confidence: 71%
See 3 more Smart Citations
“…As shown in Table 4 and reported elsewhere [ 36 ], of the cattle with positive results by to RT-PCR, both Ab-positive and-negative results were detected. The double positive status to both BVDV Ab and nucleic acid detection might indicate an acute infection stage, while that positive to nucleic acid but negative to Ab detection might suggest either an early phase of acute infection, because development of detectable Ab usually requires 1–2 weeks after infection, or a persistent infection in which Ab detection is negative, but positive for both nucleic acid and Ag detection.…”
Section: Discussionsupporting
confidence: 71%
“…The concept that Ab-positive rates are inversely correlated to Ag-positive rates has be confirmed in infections with BVDV [ 36 ] and other agents s [ 37 ]. The results of this study supported these previous findings.…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…In Korea, several investigations of the prevalence and characterizations of BVDV have been performed in cattle Oem et al, 2010;Oem et al, 2009;Park et al, 2004). However, the survey of infectious diseases in goats has rarely performed.…”
Section: Introductionmentioning
confidence: 99%