Characterization of a new external neutron beam facility at the Ohio State University

Turkoglu, Danyal J.; Burke, Joshua; Lewandowski, Radoslaw; Cao, Lei

doi:10.1007/s10967-011-1289-2

Cited by 30 publications

(12 citation statements)

References 9 publications

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“…7, where the impact of a finite neutrino magnetic moment on CEνNS spectra, and two alike models of germanium QF, are seen to compete for the interpretation of future data. In preparation for the use of p-type point contact (PPC) germanium detectors [46] in CEνNS studies, we have explored the sub-keV germanium QF, combining a new exposure to 88 Y/Be and 124 Sb/Be monochromatic neutron sources [47][48][49], with a repetition of a reactor measurement yielding 254 eV NRs [50,51], and an improved calibration using 24 keV neutrons from a filtered beam [46,52]. The picture provided by this body of new information will be the subject of a future publication.…”

Section: Discussionmentioning

confidence: 99%

Response of CsI[Na] to nuclear recoils: Impact on coherent elastic neutrino-nucleus scattering

2019

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A new measurement of the quenching factor for low-energy nuclear recoils in CsI[Na] is presented. Past measurements are revisited, identifying and correcting several systematic effects. The resulting global data are well-described by a physics-based model for the generation of scintillation by ions in this material, in agreement with phenomenological considerations. The uncertainty in the new model is reduced by a factor of four with respect to an energy-independent quenching factor initially adopted as a compromise by the COHERENT collaboration. A significantly improved agreement with Standard Model predictions for the first measurement of CEνNS is generated. We emphasize the critical impact of the quenching factor on the search for new physics via CEνNS experiments.

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Section: Discussionmentioning

confidence: 99%

Response of CsI[Na] to nuclear recoils: Impact on coherent elastic neutrino-nucleus scattering

2019

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“…An ideal beam for this mode of calibration is available at The Ohio State University Research Reactor (OS-URR). Single-crystal sapphire and polycrystalline bismuth are used for fast neutron and gamma filtering of core radiations, respectively, resulting in a high-purity thermal neutron beam ∼3 cm in diameter with flux selectable in the range 10 4 -10 7 n/cm 2 s. Its cadmium ratio is 266, i.e., there are just 3.76 neutrons with energies higher than 0.4 eV for every 1,000 thermals [49].…”

Section: Recoils From Gamma Emission Following Thermal Neutron Capturementioning

confidence: 99%

Germanium response to sub-keV nuclear recoils: a multipronged experimental characterization

Collar,

Kavner,

Lewis

2021

Preprint

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Germanium is the detector material of choice in many rare-event searches looking for low-energy nuclear recoils induced by dark matter particles or neutrinos. We perform a systematic exploration of its quenching factor for sub-keV nuclear recoils, using multiple techniques: photo-neutron sources, recoils from gamma-emission following thermal neutron capture, and a monochromatic filtered neutron beam. Our results point to a marked deviation from the predictions of the Lindhard model in this mostly unexplored energy range. We comment on the compatibility of our data with low-energy processes such as the Migdal effect, and on the impact of our measurements on upcoming searches.

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“…In general, neutrons are much more effective in destroying tumor cells than radiation with low linear energy transfer (LET), such as gamma, X, electron, etc. (26). The results of calculating the fast neutron flux around the source by two methods of simulation with MCNPX and detection with BF3, showed that with increasing the distance from the source, the Fast neutron flux decreased exponentially.…”

Section: 5discussionmentioning

confidence: 98%

Comparative study of the effect of neutrons emitted from neutron source ²⁴¹Am-Be and curcumin on MCF-7 breast cancer cells in 3D culture medium

Zargan

Barough

Zargan

et al. 2022

Preprint

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Introduction: Cancer is one of the major medical problems threatening human health. Breast cancer is the most prevalent type of cancer in women. For more efficient treatment, new treatment strategies have been evolved based on combination therapy in which two or more different methods are exploited for this aim. In the present study, a combination therapy based on radiotherapy (using neutron radiation emitted from a Am-Be neutron source) and biotherapy (using curcumin) is applied to investigate the treatment efficiency of MCF-7 breast cancer in a three-dimensional culture medium. Materials and methods: MTT, neutral red uptake assay, nitric oxide, glutathione assay, catalase, cytochrome c, comet assay, and caspase-3 were used to determine the effect and type of mortality due to neutron effect as well as the combined effect of neutron and curcumin in cancer cells. Results: The results of cytotoxicity due to neutron irradiation as well as the combined effect of neutron and curcumin showed that neutron irradiation with or without curcumin at 5, 10, 15, and 20 hours reduced the survival of tumor cells. Conclusion: Overall, this study showed that the neutron source Am-Be with the applied doses was able to destroy the co, and ch bonds of curcumin, resulting in cell death and apoptosis induction in breast cancer cells. It was caused by neutron radiation. Due to the significant anti-cancer effect of curcumin in 3D culture, the use of this molecule before or after neutron therapy is recommended.

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Characterization of a new external neutron beam facility at the Ohio State University

Cited by 30 publications

References 9 publications

Response of CsI[Na] to nuclear recoils: Impact on coherent elastic neutrino-nucleus scattering

Response of CsI[Na] to nuclear recoils: Impact on coherent elastic neutrino-nucleus scattering

Germanium response to sub-keV nuclear recoils: a multipronged experimental characterization

Comparative study of the effect of neutrons emitted from neutron source ²⁴¹Am-Be and curcumin on MCF-7 breast cancer cells in 3D culture medium

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Characterization of a new external neutron beam facility at the Ohio State University

Cited by 30 publications

References 9 publications

Response of CsI[Na] to nuclear recoils: Impact on coherent elastic neutrino-nucleus scattering

Response of CsI[Na] to nuclear recoils: Impact on coherent elastic neutrino-nucleus scattering

Germanium response to sub-keV nuclear recoils: a multipronged experimental characterization

Comparative study of the effect of neutrons emitted from neutron source 241Am-Be and curcumin on MCF-7 breast cancer cells in 3D culture medium

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Comparative study of the effect of neutrons emitted from neutron source ²⁴¹Am-Be and curcumin on MCF-7 breast cancer cells in 3D culture medium