Characterization of chicken muscle disorders through metabolomics, pathway analysis, and water relaxometry: a pilot study

Integrated metabolomics and lipidomics evaluate the alterations of flavor precursors in chicken breast muscle with white striping symptom

“…In this study, AMP/GMP, xanthosine and GDP-fucose increased significantly and fructose 1,6-bisphosphate decreased significantly in the WS meat. By One-dimensional 1 H-NMR, previous research showed that malonate, taurine, threonine, and arginine were important metabolites for distinguishing normal breast from severe WS ( Cônsolo et al, 2020 ). The inconsistency results showed in two studies may be related to the different analysis methods and the sample conditions.…”

Proteomic analyses on chicken breast meat with white striping myopathy

“…To understand the etiology, genetic susceptibility, gene and protein expression, and biochemical pathways associated with breast myopathies, including WS and WB meat, researchers have extensively used genomics ( Alnahhas et al, 2016 ; Pampouille et al, 2018 ), transcriptomics ( Mutryn et al, 2015 ; Marchesi et al, 2019 ; Maharjan et al, 2021 ), proteomics ( Kuttappan et al, 2017 ; Cai et al, 2018 ; Zhang et al, 2020a ; Zhang et al, 2020b ), metabolomics ( Abasht et al, 2016 ; Boerboom et al, 2018 ; Consolo et al, 2020 ), and other methodologies ( Abasht et al, 2021 ; Bordini et al, 2022 ; Bordini et al, 2021 ; Kong et al, 2021 ). Transcriptomics with WS meat identified differentially expressed genes associated with hypoxia, cell death, angiogenesis, immune system, and striated muscle contraction ( Marchesi et al, 2019 ).…”

A comparative study to determine the effects of breed and feed restriction on glucose metabolism of chickens

“…In addition, dietary restriction is widely used in both human and animal production to control body weight (BW) and avoid many obesity-related diseases to improve metabolic adaptability ( Murphy et al, 2012 ), glucose balance, lipid distribution, and cardiovascular health ( Walford et al, 1992 ; Heilbronn et al, 2006 ). As far as chickens are considered, they have undergone intensive genetic selection for approximately 60 generations for rapid growth ( Cônsolo et al, 2020 ). One unwanted side effect of this genetic gain is the increase in the incidence of metabolic disorders ( Sumners et al, 2014 ).…”