Characterization of cyclotriveratrylene inclusion compounds by means of solid state13C NMR

Burlinson, N. E.; Ripmeester, John A.

doi:10.1007/bf00665483

Cited by 16 publications

(19 citation statements)

References 10 publications

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“…Cyclotriveratrylene (CTV) is the parent compound of many homologous series based on the TBCN core. These compounds have gained considerable interest throughout the years because of their special (crown/saddle) conformational isomerism,18–20 structural chirality,17, 18, 21, 22 tendency to form molecular complexes23, 24 and their mesomorphic properties 14, 25, 26. Different TBCN derivatives have been previously obtained through elaborate synthetic methodologies.…”

Section: Introductionmentioning

confidence: 99%

Identification of a NCR⁺/NKG2D⁺/LFA‐1^low/CD94⁻ immature human NK cell subset

et al. 2009

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CD56bright natural killer (NK) cells, generated in vitro from CD34 1 hematopoietic progenitor cells, were characterized after a 30-day culture with flt3 ligand plus IL-15. Virtually, all CD56 bright cells expressed CD117, CD25, natural cytotoxicity receptors (NCRs), NKG2D, CD161, and CD244, while only a subset expressed CD18-CD11a (LFA-1), and CD94 molecule, defining an immature CD56 and activatory function that finely control their functional activities. In particular, they express inhibitory receptors for MHC class I (MHC-I) molecules, named killer cell immunoglobulin (Ig)-like receptors (KIRs) and C-type lectin CD94-CD159a, and many triggering molecules like NKp30, NKp44, NKp46, (called natural cytotoxicity receptors, NCRs), NKG2D, CD161, and CD244 (1-4). The majority of peripheral blood (PB) human NK cells are characterized by a phenotype with a low density expression of CD56 (CD56 dim ) and a high expression of CD16 (CD16 bright ), whereas a minority (approximately 5-10%) shows a bright expression of CD56 (CD56 bright ). This latter NK subset presents relatively high expression of some cytokine receptors (CD117 and CD25), lymph node homing receptors (CD62L and CCR7) and the CD94-CD159a heterodimeric inhibitory receptor. Moreover, differently from the well-known CD56 dim /CD16 bright cells, only a small percentage of the CD56 bright subset expresses KIR inhibitory receptors (5-10%) and CD16 dim (20-30%) while, in the majority, these antigens are not expressed (5). On the other hand, CD56bright NK cells are widely expressed in lymphoid tissues (6) and can be generated from CD34 1 cells when cultured with combinations of flt-3 ligand (FL) or stem cell factor plus IL-15 or IL-2 (7-10). During their development, NK cells sequentially acquire many different antigens and some of them allow to distinguish intermediate stages of NK cell differentiation. We had already taken advantage of CD161 antigen expression to define an immature CD161 1 /CD56 2 subset able to kill Jurkat cells via a TRAIL-dependent mechanism (3,11). When cultured with IL-12, this NK cell subset began to express CD56 molecule and became cytotoxic against K562 cells, thus suggesting a

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Section: Introductionmentioning

confidence: 99%

Identification of a NCR⁺/NKG2D⁺/LFA‐1^low/CD94⁻ immature human NK cell subset

et al. 2009

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“…CTV has been extensively studied for its capability to bind a variety of small organic and organometallic guests within its bowl-shaped cleft. [13][14][15] Many clathrates of CTV have been structurally characterized, including DMSO and ethanol 16 , chlorinated organics 17 , xenon 18 , lanthanides 19 organometallic complexes, 20 C60, 21 and anionic C70 dimers. 22 CTV has also been used for selective anion sensing, 23 and thioether derivatives of CTV have recently been employed as hosts to immobilize C60 onto gold surfaces.…”

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confidence: 99%

Isolation of the saddle and crown conformers of cyclotriveratrylene (CTV) oxime

Lutz

French

Rehage

et al. 2007

Tetrahedron Letters

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“…This [1.1.1]orthocyclophane is readily prepared from the trimerization of veratryl alcohol in acid and has been extensively studied for its capability of binding a variety of smaller organic and organometallic guests within its bowlshaped cleft. [2][3][4] Many clathrates of CTV [5][6][7][8][9] and of CTV derivatives 5 have been structurally characterized including clathrates with anionic C70 dimers. 10 Thioether derivatives of CTV have recently been employed to immobilize C60 onto gold surfaces, 11,12 and water soluble CTV derivatives have been developed for biomedical applications including the biological delivery of fullerenes.…”

Section: Graphical Abstractmentioning

confidence: 99%