Characterization of Functional Changes in Macular Holes and Cysts

Acosta, Fernando; Lashkari, Kameran; Reynaud, X.; Jalkh, Alex E.; Velde, Frans Van De; Chedid, Nabil

doi:10.1016/s0161-6420(91)32044-x

Cited by 74 publications

(24 citation statements)

References 7 publications

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“…If microsaccades were of no importance to the visual process, one would expect that mean microsaccadic amplitude individually was unaffected by visual acuity-an allegation supported by a previous monocular study from our group showing no correlation between changes in visual acuity and changes in mean microsaccadic amplitude after photocoagulation for clinically significant oedema. However, a negative correlation between visual acuity and microsac- cadic amplitude was found in the present binocular study, a result in accordance with previous studies on diabetic and non-diabetic patients obtained during monocular fixation [1,4,25]. Furthermore, recent studies have shown that microsaccades profoundly influence the activity of neurones in the lateral geniculate nucleus and visual cortex [18,[20][21][22].…”

Section: Discussionsupporting

confidence: 93%

Binocular fixation topography in patients with diabetic macular oedema

Møller

Laursen

Sjølie

2005

Graefe's Arch Clin Exp Ophthalmol

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Large interindividual differences in quantitative measures of binocular fixational eye movements were found. The mean amplitude of fixational eye movements was not correlated to central retinal thickness, and fixation area could only partly be predicted by visual acuity. Two eyes with CSME had an estimated maximal extension of the fixation area exceeding the central 800 mum on the retinal plane; thus, the possible benefit of individualising central photocoagulation according to precise measures of fixation area needs to be investigated on a larger population.

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Section: Discussionsupporting

confidence: 93%

Binocular fixation topography in patients with diabetic macular oedema

Møller

Laursen

Sjølie

2005

Graefe's Arch Clin Exp Ophthalmol

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“…Although these tests include the visual field of the macular area, microperimeters like the scanning laser ophthalmoscope (SLO; Rodenstock, Ottobrunn, Germany) and the MP-1 (Nidek Technologies, Vigonza, Italy) may be better for the central 5° [1,2] . The SLO evaluates the correlation between the morphologic appearance of the fundus and its function [2,3] . Visual fields using the SLO show reliable measurements in a range comparable to conventional computerized perimetry.…”

Section: Introductionmentioning

confidence: 99%

Values for Macular Perimetry Using the MP-1 Microperimeter in Normal Subjects

Shah

Chalam

2008

Ophthalmic Res

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Purpose: To establish values for the fixation pattern and macular sensitivity to light in healthy subjects using the MP-1 microperimeter (Nideck Technologies, Vigonza, Italy). Method: A prospective study of 37 healthy subjects (age: 19–71 years), approved by the institutional review board. Full-threshold microperimetry of the central 12° of the retina (the macula) was performed prospectively, utilizing 16 points with the MP-1. The fixation stability was simultaneously recorded during microperimetry testing. The relationship between the fixation pattern and light sensitivity with age was calculated using linear regression analysis. Results: Microperimetry was performed on 66 eyes. Total mean sensitivity was 18.33 dB (range: 13.0–19 dB). Mean macular sensitivities at 2°, 4° and 6° as measured by the MP-1 were 18.4 ± 2.0, 18.2 ± 2.3 and 18.2 ± 2.1 dB, respectively. The linear regression analysis revealed a 0.019240, 0.0248 and 0.0285 dB per year age-related decline in mean macular sensitivity at 2°, 4° and 6° from the center of the macula, respectively. The total mean fixation stability values within 2° and 4° were 86 and 96%, respectively. The linear regression analysis also revealed a 0.344% and 0.122% per year decline in age-related fixation stability within 2° and 4°, respectively. There were no statistically significant differences between the median retinal sensitivity or fixation stability values for sex or race in the study. Conclusions: The MP-1 may be a reliable tool to measure macular sensitivity. Among normal healthy subjects, there was a linear decline in light sensitivity with increasing age.

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“…Consideraram-se como critérios de inclusão: idade igual ou superior a 50 anos; diagnóstico clínico de DMRI; entendimento e assinatura do termo de consentimento livre e esclarecido; serem pacientes alertas, cooperativos, com boa coordenação motora manual; padrão de fixação nível 2 (apresenta um local de preferência para fixação na retina, apesar de algumas perdas transitórias) ou fixação nível 3 (fixação está-vel), conforme padrões estabelecidos por Acosta et al (5) . Foram considerados critérios de exclusão: ametropia maior que seis graus; deficiência de visão de cores; doenças oculares que pudessem afetar o campo visual (glaucoma, retinocoroidopatia serosa central, oclusão de vaso retiniano, diabetes melito, neuropatia óptica isquêmica, rotura de coróide e outras), pacientes em uso de drogas que podem afetar a função visual (cloroquina e outras), trauma ocular prévio, doenças desmielinizantes, olhos que foram tratados com laser previamente, cirurgia intraocular prévia, outra que não catarata, e relato de história de contra-indicação para o uso de midriáticos.…”

Section: Métodosunclassified