Characterization of Novel Antimicrobial Peptides from the Epidermis of Clarias batrachus Catfish

Giridharan, Bupesh; Chinnaiah, Amutha; Saravanan, Konda Mani; Parthasarathy, Sudharsan; Meenakshi Sundaram, Kishore Kumar; Tharumasivam, Siva Vijayakumar; Pankaj, Pranay Punj; Govindaraju, Archunan; Haripriya, Dayalan; Sahoo, Uttam Kumar

doi:10.1007/s10989-024-10589-8

Int J Pept Res Ther

2024

DOI: 10.1007/s10989-024-10589-8

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Characterization of Novel Antimicrobial Peptides from the Epidermis of Clarias batrachus Catfish

Bupesh Giridharan,

Amutha Chinnaiah,

Konda Mani Saravanan

et al.

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Cited by 6 publications

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Antimicrobial Peptides From Different Sources: Isolation, Purification, and Characterization to Potential Applications

Ahmed,

Saif,

Qian

2024

J of Separation Science

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Antimicrobial peptides (AMPs) are excellent promising candidates for biomedical applications owing to their structural properties, high biocompatibility, good biodegradability, and functional diversity. Unlike conventional antibiotics, AMPs have been shown to have broad‐spectrum antimicrobial activity toward Gram‐positive/negative bacteria, as well as antifungal and antiviral activity. These peptides have also been found to be cytotoxic to sperm and cancer cells. A range of AMPs has been isolated from various organisms, such as bacteria, fungi, plants, and animals. This review summarizes the latest studies on AMPs, covering their isolation, purification, and characterization as well as their potential biomedical applications and beyond.

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Antimicrobial Peptides From Different Sources: Isolation, Purification, and Characterization to Potential Applications

Ahmed,

Saif,

Qian

2024

J of Separation Science

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Progress in the Identification and Design of Novel Antimicrobial Peptides Against Pathogenic Microorganisms

Sun

2024

Probiotics & Antimicro. Prot.

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The occurrence and spread of antimicrobial resistance (AMR) pose a looming threat to human health around the world. Novel antibiotics are urgently needed to address the AMR crisis. In recent years, antimicrobial peptides (AMPs) have gained increasing attention as potential alternatives to conventional antibiotics due to their abundant sources, structural diversity, broad-spectrum antimicrobial activity, and ease of production. Given its significance, there has been a tremendous advancement in the research and development of AMPs. Numerous AMPs have been identified from various natural sources (e.g., plant, animal, human, microorganism) based on either well-established isolation or bioinformatic pipelines. Moreover, computer-assisted strategies (e.g., machine learning (ML) and deep learning (DL)) have emerged as a powerful and promising technology for the accurate prediction and design of new AMPs. It may overcome some of the shortcomings of traditional antibiotic discovery and contribute to the rapid development and translation of AMPs. In these cases, this review aims to appraise the latest advances in identifying and designing AMPs and their significant antimicrobial activities against a wide range of bacterial pathogens. The review also highlights the critical challenges in discovering and applying AMPs.

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Chitosan-chondroitin sulfate-daidzein nanoconjugate ameliorates glucocorticoid induced osteoporosis in vivo

Snega Priya,

Surisetti,

Gopi

et al. 2024

International Journal of Biological Macromolecules

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Characterization of Novel Antimicrobial Peptides from the Epidermis of Clarias batrachus Catfish

Cited by 6 publications

References 52 publications

Antimicrobial Peptides From Different Sources: Isolation, Purification, and Characterization to Potential Applications

Antimicrobial Peptides From Different Sources: Isolation, Purification, and Characterization to Potential Applications

Progress in the Identification and Design of Novel Antimicrobial Peptides Against Pathogenic Microorganisms

Chitosan-chondroitin sulfate-daidzein nanoconjugate ameliorates glucocorticoid induced osteoporosis in vivo

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