Characterization of spontaneous otoacoustic emissions in full-term newborns

Qi, Beier; Cheng, Xiaohua; En, Hui; Huang, Lihui; Zhang, Luo

doi:10.1016/j.ijporl.2014.10.035

Cited by 7 publications

(6 citation statements)

References 23 publications

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“…OAEs are also more prevalent and stronger in female newborns compared to males (Qi, Cheng, Cheng, En, Huang, & Zhang, 2014;Strickland et al, 1985); a trend which remains in adulthood (Snihur & Hampson, 2011).…”

Section: Otoacoustic Emissions (Oaes)mentioning

confidence: 99%

Age‐related hearing loss: Why we need to think about sex as a biological variable

Nolan

2020

J of Neuroscience Research

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It has long been known that age‐related hearing loss (ARHL) is more common, more severe, and with an earlier onset in men compared to women. Even in the absence of confounding factors such as noise exposure, these sexdifferences in susceptibility to ARHL remain. In the last decade, insight into the pleiotrophic nature by which estrogen signaling can impact multiple signaling mechanisms to mediate downstream changes in gene expression and/or elicit rapid changes in cellular function has rapidly gathered pace, and a role for estrogen signaling in the biological pathways that confer neuroprotection is becoming undeniable. Here I review the evidence why we need to consider sex as a biological variable (SABV) when investigating the etiology of ARHL. Loss of auditory function with aging is frequency‐specific and modulated by SABV. Evidence also suggests that differences in cochlear physiology between women and men are already present from birth. Understanding the molecular basis of these sex differences in ARHL will accelerate the development of precision medicine therapies for ARHL.

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Section: Otoacoustic Emissions (Oaes)mentioning

confidence: 99%

Age‐related hearing loss: Why we need to think about sex as a biological variable

Nolan

2020

J of Neuroscience Research

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“…Similarly, in the current study, SOAEs were identified in 86% of newborns with an average of five SOAEs per newborn. Others report that a greater number of SOAEs and higher levels are recorded in females than males [55,61,62,65,66,[71][72][73]. The number of male and female newborns with present SOAEs was similar and the average number of present SOAEs was higher in males (6.75/ear) compared to females (4.7/ear).…”

Section: Discussionmentioning

confidence: 93%

“…As spontaneous otoacoustic emissions (SOAEs) show sensitivity to cochlear damage, are present in newborns, occur at higher frequencies in newborns compared to adults, and can influence DPOAE levels [16,[55][56][57], SOAEs should be measured continuously as well in monitoring programs. SOAEs are sounds recorded from the inner ear without external stimulation.…”

Section: Introductionmentioning

confidence: 99%

“…While these differences between ears and gender for SOAEs remain unexplained, McFadden [74] suggests that these findings might be related to less efferent inhibition in females and in right ears. Additionally, some studies report that females tend to have more SOAEs than their male counterparts [55,61,66]. When recording SOAEs in newborns, Qi et al [55] reported that 56.7% of newborn ears exhibited SOAEs and they occurred at higher frequencies than adults.…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, some studies report that females tend to have more SOAEs than their male counterparts [55,61,66]. When recording SOAEs in newborns, Qi et al [55] reported that 56.7% of newborn ears exhibited SOAEs and they occurred at higher frequencies than adults. More recently, Abdala et al [54] reported that 85% of newborns have at least one SOAE, with an average of four to five SOAEs per emitting ear.…”

Section: Introductionmentioning

confidence: 99%

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Acquisition and Repeatability of High-Frequency Distortion Product Otoacoustic Emissions Using Two Different Calibration Methods in Newborns

et al. 2019

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Featured Application: The potential application of this work lies in the ability to monitor the highest frequencies evoking an otoacoustic emission to assess basal cochlear health in newborns receiving ototoxic treatments.Abstract: Distortion-product otoacoustic emissions (DPOAEs) elicited with high-frequency (HF; up to 16 kHz) stimuli are measurable and repeatable in normal-hearing adults and children, adult patients, and are sensitive to ototoxic insults in adults. However, objective tests for monitoring basal cochlear function in those too young to respond subjectively need to be developed. DPOAE levels recorded at frequencies <10 kHz are well characterized, but DPOAE levels measured up to 16 kHz do not exist for newborns. The goal of the current study is to determine if HF DPOAEs are measurable and repeatable in newborns. DPOAEs were measured from 2-16 kHz (f 2 /f 1 of 1.22; L 1 /L 2 = 65/55 dB SPL) using two different calibration methods (forward pressure level-FPL and in-the-ear-SPL) in 26 newborns. To assess repeatability, the probe was removed then re-inserted for a second round of testing. Results indicate that HF DPOAEs can be evoked and are repeatable in newborns and the use of FPL calibration shows promise for measuring HF responses and maximizing repeatability. To be implemented in monitoring programs where the highest frequencies with responses are continuously tested, stimulus parameters used to evoke newborn HF DPOAEs and calibration methods need further exploration.

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The characteristic of otoacoustic emissions in full-term neonates according to ABO blood groups

Gao

Wang

et al. 2020

Brazilian Journal of Otorhinolaryngology

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Characterization of spontaneous otoacoustic emissions in full-term newborns

Cited by 7 publications

References 23 publications

Age‐related hearing loss: Why we need to think about sex as a biological variable

Age‐related hearing loss: Why we need to think about sex as a biological variable

Acquisition and Repeatability of High-Frequency Distortion Product Otoacoustic Emissions Using Two Different Calibration Methods in Newborns

The characteristic of otoacoustic emissions in full-term neonates according to ABO blood groups

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