“…1 Therefore, SPR sensors are widely used in biochemistry, clinical diagnosis, food analysis, and environmental biology. 2,3 Several types of sensing techniques using SPR phenomena have been developed, including the Kretschmann, 4 Otto, 5 and optical fibre types 6 and localized surface plasmon resonance (LSPR) sensing. 7 Among these techniques, Kretschmann-type SPR sensing has been the most commonly used because of the simple setup for chip fabrication and sensing; it is employed in commercially available equipment from various companies, such as Biacore.…”