Characterization of V1R receptor (ora) genes in Lake Victoria cichlids

Ota, Tomoki; Nikaido, Masato; Suzuki, Haruna; Hagino-Yamagishi, Kimiko; Okada, Norihiro

doi:10.1016/j.gene.2012.03.002

Cited by 19 publications

(39 citation statements)

References 39 publications

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“…We recently characterized six V1R genes in LV cichlids using a H. chilotes BAC library (Ota et al 2012). To evaluate the variability of each V1R gene, we first analyzed genetic divergence by comparing V1R gene sequences from 17 species of LV cichlids (one individual from each species) (supplementary fig.…”

Section: Resultsmentioning

confidence: 99%

“…The repertoire of the fish V1R gene family is small (i.e., six genes in most species), and it is rigidly maintained in distantly related fish species including cichlids (Saraiva and Korsching 2007; Grus and Zhang 2009; Ota et al 2012; Nikaido et al 2013a). Genes orthologous to teleost fish V1Rs have also been found in lamprey, elephant shark, and frog, indicating that these genes have been maintained for an extremely long period during the evolution of aquatic vertebrates (>500 Myr; Grus and Zhang 2009).…”

Section: Introductionmentioning

confidence: 99%

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Multiple Episodic Evolution Events in V1R Receptor Genes of East-African Cichlids

Nikaido

Ota

Hirata

et al. 2014

Genome Biology and Evolution

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Fish use olfaction to detect a variety of nonvolatile chemical signals, and thus, this sense is key to survival and communication. However, the contribution of the olfactory sense to social—especially reproductive—interactions in cichlids is still controversial. To obtain insights into this issue, we investigated the genes encoding V1Rs—possible candidates for reproductive pheromone receptors—among East-African cichlids. Interestingly, we found an excess of nonsynonymous over synonymous substitutions in four of six V1R genes in multiple cichlid lineages. First, we found that highly dimorphic V1R2 allele groups were shared among the cichlids inhabiting all East-African Great Lakes emerged through the episodic accumulation of the nonsynonymous substitutions prior to the radiation of the Lake Tanganyika species flock. We further detected such episodic events in V1R1 of the tribe Tropheini, and in V1R3 and V1R6 of the tribe Trematocarini. The excess of nonsynonymous substitutions in these examples were indicated as dN/dS > 1, which were all statistically significant by Fisher’s exact test. Furthermore, we speculate that the amino acid changes in these episodic events are likely functional switch because they occurred in the putative ligand-binding pocket. Our finding of the occurrence of multiple episodic events and the unexpected gene diversity in one unique gene family is suggestive of the contribution of the V1R to the species diversification and the social interaction in cichlids.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Multiple Episodic Evolution Events in V1R Receptor Genes of East-African Cichlids

Nikaido

Ota

Hirata

et al. 2014

Genome Biology and Evolution

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“…4B), implying that the sex-determining loci emerged independently in cichlid LG5. Furthermore, we found that V1R1 and V1R2, which are the candidate genes for reproductive pheromone receptors in teleost fish (Nikaido et al, 2014), are both located very close to the sex-determining locus of LV cichlids (Ota et al, 2012;Fig. 4A, B).…”

Section: Highly Diversified Genes In Lg5 Of Cichlidsmentioning

confidence: 87%

“…We also used the markers TmoM5 and 7 (Zardoya et al, 1996), Ppun 1 to 41 (Taylor et al, 2002), HchiST01 to 98 (Maeda et al, 2008), and OSU9D to 22D (Wu et al, 1999). Additionally, we determined microsatellite motifs in the sequences of the BAC clones of H. chilotes (Watanabe et al, 2003) in which V1R3, V1R4, and V1R5 were included (Ota et al, 2012;Nikaido et al, 2014). We also explored SNP markers on V1R1 and V1R6.…”

Section: Microsatellite Markersmentioning

confidence: 99%

A microsatellite-based genetic linkage map and putative sex-determining genomic regions in Lake Victoria cichlids

Kudo

Nikaido

Kondo

et al. 2015

Gene

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“…Animals are also known to have many olfactory receptor genes and can distinguish many types of odor (Buck and Axel 1991). A recent study has shown that African cichlids also have and express many different olfactory receptor genes within one individual (Ota et al 2012). Thus, our assumption that each allele independently expresses a different sensory trait would be more realistic than the model that assumes the additive determination of one sensory trait.…”

Section: Application To Other Organismsmentioning

confidence: 99%

Sensory drive speciation and patterns of variation at selectively neutral genes

et al. 2014

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Speciation by sensory drive can occur if divergent adaptation of sensory systems causes rapid evolution of mating traits and the resulting development of assortative mating. Previous theoretical studies have shown that sensory drive can cause rapid divergent adaptive evolution from one to two phenotypes. In this study, we examined two topics: the possibility of adaptive radiation by sensory drive from one to more than two phenotypes and the relationships of patterns of variation at selectively neutral genes to levels of viability selection, habitat and mating preferences and migration. We conducted individual-based simulations assuming a sensory trait and a mating trait controlled by a small number of loci. We found that adaptive radiation is possible when the number of loci controlling the sensory trait is small; the levels of viability selection, habitat and mating preferences are intermediate; and the emigration rate is high. We also found that emigration rates as well as the levels of habitat and mating preferences are related to 123Evol Ecol (2014) 28:591-609 DOI 10.1007 values at neutral loci, but F ST proved to be insensitive to a small change in the number of loci controlling the mating trait. This suggests that an estimation of the past population history is possible without an accurate genetic model.

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Characterization of V1R receptor (ora) genes in Lake Victoria cichlids

Cited by 19 publications

References 39 publications

Multiple Episodic Evolution Events in V1R Receptor Genes of East-African Cichlids

Multiple Episodic Evolution Events in V1R Receptor Genes of East-African Cichlids

A microsatellite-based genetic linkage map and putative sex-determining genomic regions in Lake Victoria cichlids

Sensory drive speciation and patterns of variation at selectively neutral genes

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