Characterization of women with a history of recurrent vulvovaginal candidosis

Abstract

Characterization of women with a history of recurrent vulvovaginal candidosis.Novikova, Natalia; Mårdh, Per-Anders Published in: Acta Obstetricia et Gynecologica Scandinavica DOI: 10.1034/j. 1600 -0412.2002 .811109.x Published: 2002 Link to publication Citation for published version (APA): Novikova, N., & Mårdh, P-A. (2002). Characterization of women with a history of recurrent vulvovaginal candidosis. Acta Obstetricia et Gynecologica Scandinavica, 81(11), 1047-1052. DOI: 10.1034/j.1600-0412.2002 General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research.• You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal Take down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Background. To characterize history, signs, and symptoms in women with a history of recurrent vulvovaginal candidosis (RVVC) and who had consulted with symptoms generally associated with the condition. Methods. Eighty-three women with a history consistent with RVVC were interviewed regarding 32 parameters and 10 signs found at the clinical examination were noted. Candida cultures were made from the introitus and the posterior vaginal fornix.Results. Only in a few of the 43 women with and the 40 without a positive yeast culture could any of the many etiological factors that have been associated with RVVC be traced. Only two factors differed between the groups, namely yogurt intake, which was reported by 28 (68%) and 38 (95%) women in these groups, respectively. Vaginal douching was performed by 10 (23%) women in the Candida-positive group and by 17 (42%) women in the Candidanegative group. Pruritis and burning occurred in 31 (72%) and 22 (51%) of culture-positive patients, which was less frequent than in the culture-negative group, i.e. reported by 19 (47%) and 9 (22%) patients, respectively (p Ω 0.022 and p Ω 0.007). Edema (p Ω 0.026) of the vulva as well as erythema (p Ω 0.019) and edema (p Ω 0.008) of the vaginal mucosa, caseous discharge (p Ω 0.016), were found more often in the Candida culture-positive cases. Conclusions. History and results of clinical examination of patients with RVVC are not enough to distinguish those who are culture-positive from those who are culture-negative for Candida from the genital tract.

Colonisation of extragenital sites by Candida in women with recurrent vulvovaginal candiosis

“…The women were interviewed about their clothing, use of hormonal contraceptives and intimate hygiene products, as well as about their practice of oral and anal intercourse. These data have been reported elsewhere in relation to genital colonisation with Candida 7 . Here we report on colonisation of extragenital sites.…”

“…The low rate of oral candidosis in our study suggests that Candida was a part of the indigenous flora. Oral candidosis is more common in women taking oral contraception 11 ; in our study, only five women used this form of contraception 7 .…”

“…The positive cultures may have represented organisms from the lower urinary tract, but also contamination from the introitus. One‐quarter of the women who were culture‐positive for Candida complained of a burning sensation when passing urine 7 .…”

Colonisation of extragenital sites by Candida in women with recurrent vulvovaginal candiosis

“…The positive cultures may have represented organisms from the lower urinary tract, but also contamination from the introitus. One-quarter of the women who were culturepositive for Candida complained of a burning sensation when passing urine 7 .…”

Leukocyte Esterase Activity in Vaginal Fluid of Pregnant andNon‐Pregnant Women With Vaginitis/Vaginosis and in Controls

“…patients who had had at least four attacks of the condition during the previous year, and who had consulted with symptoms suggesting a new attack of RVVC. The diagnostic criteria applied have been described in detail elsewhere 13,14 . The number of these women who had a positive LE test has already been reported in a previous study 13 .…”