Characterization, quantum, antibacterial, antifungal and antioxidant studies on Hg(II) and Cd(II) complexes of allyl and ethyl thiosemicarbazides derived from 2-aminothiazole-4-yl acetohydrazide

Abstract

e g y p t i a n j o u r n a l o f b a s i c a n d a p p l i e d s c i e n c e s 3 (2 0 1 6) 4 4-6 0

Design, synthesis, characterization and antimicrobial evaluation of some novel hydrazinecarbothioamide, 4‐thiazolidinone and 1,2,4‐triazole‐3‐thione derivatives

“…Thiosemicarbazide moiety bearing compounds have been considered as biologically important since their wide range of reported biological activity such as antibacterial, [41,42] antifungal, [43] antitubercular, [44] anticonvulsant, [45] anticancer, [46,47] cytotoxic [42] and antioxidant [48] . Thiosemicarbazide moiety is not only important because of their potential activity but also their ability to be used as starting compounds for the synthesis of diverse biologically potent moieties such as 1,2,4-triazole-3-thiones, [48] 4-thiazolidinones, [49] 1,3,4-oxadiazoles [11] and 1,3,4-thiadiazoles.…”

Biological Applications of Co(II) and Ni(II) Complexes of Semicarbazones and Thiosemicarbazones

“…The biological importance of these Schiff's base chelates of thiosemicabazides involved the researchers greater than before to develop fresh ligands as antibacterial [16], antimicrobial [17][18][19], antifungal [20,21], antiparasitic [22], antitumor [23], anticancer [24][25][26], antioxidant [27,28], anti-inflammatory [29], anti-HIV [30], antiproliferative [31], antileishmanial activities [32] and antiviral [33]. Tetradentate thiosemicabazone with strong DNA-binding ability was isolated after the condensation of pyruvaldehyde with 4-(aryl)-thiosemicarbazones [34].…”

Porcine skin gelatin–silver nanocomposites: synthesis, characterisation, cell cytotoxicity, and antibacterial properties

“…Subsequently, 30 μl of the synthesised PSG-AgNPs solutions were poured into 5 mm wells made on the NA plates. The plates were incubated at 37°C for 24 h, and the clear zones were measured [36][37][38]. All the tests were performed in triplicate, and the standard error of the mean of the zone of inhibition (ZI) and the clear zone around each well (mm) was measured.…”