Characterizing the paramagnetic behavior of Cu2+ doped nickel(II) dipicolinato by using theoretical and experimental EPR and UV–vis studies

Yıldırım, İlkay; Çelik, Yunus; Karabulut, Bünyamin

doi:10.1016/j.physb.2015.12.032

Cited by 2 publications

(1 citation statement)

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“…After the phenolic hydroxyl groups on the dopamine formed a complex with the metal ions, the protons on the ligands were replaced by metal ions, forming lone pair electrons. Cu 2+ , which contains unpaired electrons, is a paramagnetic metal ion [46]. Under the influence of Cu 2+ , the 1 H-NMR peaks of the dopamine groups disappeared (Figure 4B) [47].…”

Section: Drug Loading Entrapment Efficiency and Solubilization Properties Of Ha-dop-cu-mpmentioning

confidence: 98%

Redox-Responsive Coordination Polymers of Dopamine-Modified Hyaluronic Acid with Copper and 6-Mercaptopurine for Targeted Drug Delivery and Improvement of Anticancer Activity against Cancer Cells

Tao

Yin

2020

Polymers

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Dopamine-modified hyaluronic acid (HA-DOP) was chosen as the drug carrier in this study, and Cu2+ was selected from among Cu2+, Zn2+, Fe2+, and Ca2+ as the central atom. 6-Mercaptopurine (6-MP) was conjugated with HA through a coordination reaction. HA-DOP-copper-MP (HA-DOP-Cu-MP), a redox-responsive coordination polymer prodrug, was prepared. The drug loading was 49.5 mg/g, the encapsulation efficiency was 70.18%, and the particle size was 173.5 nm. HA-DOP-Cu-MP released rapidly in the release medium containing reduced glutathione (GSH), and the accumulated release exceeded 94% in 2 h. In the release medium without GSH, the drug release rate was slow, with only 15% of the 6-MP released in 24 h. Cell uptake experiments revealed the CD44 targeting of HA. Cell viability assays showed that the cytotoxicity of HA-DOP-Cu-MP was higher than that of free 6-MP. Indeed, HA-DOP-Cu-MP is very toxic to cancer cells. In this paper, the redox-responsive drug delivery system was synthesized by a coordination reaction. The tumour targeting and tumour cytotoxicity of 6-MP were improved.

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Section: Drug Loading Entrapment Efficiency and Solubilization Properties Of Ha-dop-cu-mpmentioning

confidence: 98%

Redox-Responsive Coordination Polymers of Dopamine-Modified Hyaluronic Acid with Copper and 6-Mercaptopurine for Targeted Drug Delivery and Improvement of Anticancer Activity against Cancer Cells

Tao

Yin

2020

Polymers

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A comparative study on the local structures of the V⁴⁺ and Cu²⁺ centers in WO₃

Zhang

Zhou

Feng

et al. 2023

Zeitschrift Für Naturforschung A

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The local structures and electron paramagnetic resonance (EPR) parameters (the g factors g i and the hyperfine structure constants A i , with i = x, y, z) of the V4+ and Cu2+ centers in WO3 were theoretically investigated based on the perturbation formulas of the EPR parameters for 3d1 and 3d9 ions under rhombically compressed and elongated octahedra, respectively. In these formulas, the adopted crystal-field parameters (CFPs) are obtained from the superposition model which enables connection of the CFPs and hence the EPR parameters to the rhombic distortion. Based on the calculations, the impurity-ligand distances of the studied [VO6]8− (or [CuO6]10−) cluster are found to suffer the axial compression (or elongation) δz of about 0.098 Å (or 0.132 Å) along the z-axis, and the additional planar bond length variation δr (≈0.052 or 0.047 Å) along x- and y-axis, respectively, due to the Jahn–Teller (JT) effect.

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Characterizing the paramagnetic behavior of Cu2+ doped nickel(II) dipicolinato by using theoretical and experimental EPR and UV–vis studies

Cited by 2 publications

References 32 publications

Redox-Responsive Coordination Polymers of Dopamine-Modified Hyaluronic Acid with Copper and 6-Mercaptopurine for Targeted Drug Delivery and Improvement of Anticancer Activity against Cancer Cells

Redox-Responsive Coordination Polymers of Dopamine-Modified Hyaluronic Acid with Copper and 6-Mercaptopurine for Targeted Drug Delivery and Improvement of Anticancer Activity against Cancer Cells

A comparative study on the local structures of the V⁴⁺ and Cu²⁺ centers in WO₃

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Characterizing the paramagnetic behavior of Cu2+ doped nickel(II) dipicolinato by using theoretical and experimental EPR and UV–vis studies

Cited by 2 publications

References 32 publications

Redox-Responsive Coordination Polymers of Dopamine-Modified Hyaluronic Acid with Copper and 6-Mercaptopurine for Targeted Drug Delivery and Improvement of Anticancer Activity against Cancer Cells

Redox-Responsive Coordination Polymers of Dopamine-Modified Hyaluronic Acid with Copper and 6-Mercaptopurine for Targeted Drug Delivery and Improvement of Anticancer Activity against Cancer Cells

A comparative study on the local structures of the V4+ and Cu2+ centers in WO3

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A comparative study on the local structures of the V⁴⁺ and Cu²⁺ centers in WO₃