Cheilitis glandularis in albinos: a report of two cases and review of histopathological findings after therapeutic vermilionectomy

Lourenço, Sílvia Vanessa; Gori, Leonardo; Boggio, Paula; Nico, Marcello M. S.

doi:10.1111/j.1468-3083.2007.02159.x

Cited by 15 publications

(28 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…10 The clinical changes of CG in these 6 individuals were, in general, more significant than in most of the non-albino patients. Extreme ultraviolet sensitivity with lip sun damage may have predisposed to secondary salivary gland changes.…”

Section: Discussionmentioning

confidence: 96%

Cheilitis glandularis: A clinicopathological study in 22 patients

Nico

Melo

Lourenço

2010

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 96%

Cheilitis glandularis: A clinicopathological study in 22 patients

Nico

Melo

Lourenço

2010

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

“…Elsôsorban közép-korú (40-50 év közötti) férfiakon látjuk (80). Világvi-szonylatban nem figyeltek meg földrész-vagy országspe-cifikus megoszlást, úgy tûnik azonban, hogy világos bôrû (különösen albino) egyéneknél gyakoribb (34,46). Fiataloknál, gyermekeknél is leírták (83).…”

Section: Cheilitis Glandularisunclassified

“…szimultán, alsó és felsôajak (34), Lederman mindkét ajak (17-30%) és a buccák (30), míg má-sok kizárólag a felsô ajkon, Williams pedig a palatumon elhelyezkedô kórformákról tesznek említést. Utóbbi szerzôk az ajkakon kívül kialakuló, krónikus kisnyálmirigyek gyulladásával együtt járó, hasonló klinikai és hisztológiai tüneteket mutató elváltozásokat "stomatitis glandularisnak" nevezik (79).…”

Section: Klinikumunclassified

The differential diagnosis of cheilitis

Németh¹

2012

BVSZ

View full text Add to dashboard Cite

show abstract

“…2,3 The cause and pathogenesis of CG is unknown, but the possible participation of a true inflammatory origin versus a clinical reaction pattern to external factors such as UV light has been debated in the literature. The disease is clinically characterized by variable degrees of macrocheilia associated with red dilated ostia of excretory minor salivary gland ducts that open ectopically on the vermilion area.…”

Section: Introductionmentioning

confidence: 99%

“…1,2 CG occurs more frequently in fair-skinned adults; albino patients seem particularly prone, suggesting that sunlight may play a role on the disease onset, development, and outcome. [2][3][4]6 In recent years, reflectance confocal microscopy (RCM) has been used as a tool for "in vivo" characterization of various skin diseases. 2,4 Recent insights on the mechanisms of the disease have implicated the altered expression of water transportation channels-the aquaporins-in ductal and acinar structures of labial salivary glands.…”

Section: Introductionmentioning

confidence: 99%

In Vivo Reflectance Confocal Microscopy Evaluation of Cheilitis Glandularis

Lourenço

Kos²,

Nunes

et al. 2015

The American Journal of Dermatopathology

View full text Add to dashboard Cite

Cheilitis glandularis (CG) is an uncommon condition of unknown origin; it is clinically characterized by variable degrees of macrocheilia associated with red dilated ostia of minor salivary glands on the vermilion area, which secrete viscous saliva. Histopathological characteristics of CG are comprised of chronic sialadenitis with engorged acinar lobules and dilated ducts; CG also features chronic sun damage (actinic cheilitis and squamous cell carcinoma). These changes may be localized, and a punch biopsy specimen might fail to reveal enough criteria to support the diagnosis of CG. Reflectance confocal microscopy (RCM) is a noninvasive imaging technique that enables an in vivo en face visualization of tissues with a resolution close to conventional histopathology. Its use allows analysis of the entire lip, without excision. We reported the evaluation of 5 cases of CG based on clinical RCM and histopathological correlation. RCM examination of the lip vermilion mainly revealed a bright aspect of the superficial epithelial layers, which corresponded to labial keratosis. Alteration of the classical epithelial honeycomb pattern was observed in RCM, which corresponded to epithelial changes in actinic cheilitis at histopathology. Round, dark empty spaces intermingling the epithelium, corresponded to the ectopic excretory salivary gland ducts that open their ostia within the lip vermilion. In the lamina propria, the most striking feature was superficial salivary gland lobules, seen as dark gray lobular structures. Our study, demonstrated the use of RCM in the evaluation of CG, showing that a correlation between the clinical, digital RCM images and histopathology improved the diagnostic skills in CG evaluation.

show abstract

Cheilitis glandularis in albinos: a report of two cases and review of histopathological findings after therapeutic vermilionectomy

Cited by 15 publications

References 12 publications

Cheilitis glandularis: A clinicopathological study in 22 patients

Cheilitis glandularis: A clinicopathological study in 22 patients

The differential diagnosis of cheilitis

In Vivo Reflectance Confocal Microscopy Evaluation of Cheilitis Glandularis

Contact Info

Product

Resources

About