Cheilitis glandularis: A clinicopathological study in 22 patients

Cheilitis glandularis (CG) is a rare disorder characterized by swelling of the lip with hyperplasia of the labial salivary glands. CG is most frequently encountered in the lower lip, in middle-aged to older Caucasian men; however Asian cases were rarely reported. In this paper we present two cases of CG in Asian-Japanese men. One was a 23-year-old male with CG of the superficial suppurative type. The other was a 54-year-old male with deep suppurative type. We also reviewed the Japanese cases of CG in the literature and discussed about clinical feature of Japanese CG.

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“…In some cases, CG may degenerate into squamous cell carcinoma [5, 16, 17]. However, like our first case, it is sometimes self-healing.…”

Section: Discussionmentioning

confidence: 74%

“…Cheilitis glandularis is most frequently encountered in the lower lip, in middle-aged to older Caucasian men [4, 5]; Japanese cases are very rare. In this paper we present two cases of CG in Asian-Japanese men.…”

Section: Introductionmentioning

confidence: 99%

Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases

et al. 2011

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“…The main causes of CG are syphilis, bacterial infection, solar radiation, tobacco, poor oral hygiene and genetic factors. 71,72 Transformation of CG into SCC has been found by Nico et al 73 and Butt et al 74 Generally, a significant percentage of patients (18–36%) have been associated with the development of SCC of overlying epithelium of the lip. 75 …”

Section: Introductionmentioning

confidence: 91%

Oral Potentially Malignant Disorders: An Overview of More than 20 Entities

Mortazavi

Baharvand

Mehdipour

2014

Journal of Dental Research

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“…Glandular keilit yaşlı erkeklerde görülen alt dudakta kalıcı AE görünümünde hipertro ve acıma veya batma hissi ile karakterize nadir bir tablodur. Yakından bakıldığı zaman kırmızı mukozal makular dökülere neden olan in amasyonlu salgı bezi kanalları belirlenir 61 . Artmış kollagen ve glikozaminoglikan in ltrasyonu ile karakterize çok nadir görülen sklerödem (Buschke hastalığı) tablosunda kalıcı periorbital ödem izlenebilir 56 .…”

Section: Ayırıcı Tanıunclassified

Angioedema: Diagnosis and treatment approaches

Güneş¹,

Akarsu²

2013

TURKDERM

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ÖzetAnjiyoödem (AE) deri ve/veya mukozaların ani başlangıçlı geçici lokalize ödemi olarak tanımlanır. Bu şişme tablosu subkutan ve submukozal dokulardaki postkapiller venüllerin geçirgenliğini arttıran çeşitli vazoaktif mediyatörlerin aracılığıyla oluşan interstisyal ödem sonucunda meydana gelir. Deriye lokalize olduğunda asimetrik, gode bırakmayan, yer çekimiyle yer değiştirmeyen ve bazen ağrılı olabilen şişme ile karakterizedir. Bununla birlikte laringeal ödem ve barsak tutulumu gibi mukozal ataklar şiddetli rahatsızlığa ve hayati tehlike oluşturan semptomlara yol açabilir. Çeşitli AE formları arasında C1 inhibitör geninin disfonksiyonu veya eksikliği ile ilişkili AE (klasik herediter AE tipleri ve edinsel AE), allerjik AE, ilaçlarla ilişkili AE (steroid dışı antiinflamatif ilaçlara bağlı AE, anjiyotensin dönüştürücü enzim inhibitörlerine bağlı AE), idiyopatik AE ve yakın zamanda tanımlanan tip 3 herediter AE bulunmaktadır. Bu değişik AE formlarında örtüşen semptomlar olabilmekle birlikte bazı özgün klinik ve öykü özellikleri yanında eşlik eden ürtikaryanın varlığı ayırıcı tanıda yardımcı olabilir. AE benzeri tabloları dışlamak, tetikleyici faktörleri saptamak ve uzaklaştırmak, atakları erken farketmek ve gerekli olduğunda agresif solunum yolu açıklığını sağlamak başarılı tedavinin temelini oluşturur. Bu makalede AE'nın sık ve nadir görülen formları yanında klinik semptomları, ayırıcı tanıları ve tedavi yaklaşımları derlenmiştir. (Türk derm 2013; 47: 7-18) Anah tar Ke li me ler: Anjiyoödem, tanı, ayırıcı tanı, tedavi Sum maryAngioedema (AE) is defined as sudden, localized and transient swelling of the skin and/or mucous membranes. This swelling condition is a result of interstitial edema from vasoactive mediators increasing the permeability of postcapillary venules of the subcutaneous and submucosal tissues. When localized to the skin, it presents as asymmetric, nonpitting, nondependent, and occasionally painful edema. However, mucosal attacks, such as laryngeal edema and bowel involvement can produce severe discomfort and life-threatening symptoms. There are several forms including those involving dysfunction or depletion of the C1-inhibitor gene (classical hereditary AE types and acquired AE), allergic AE, drug-induced AE (nonsteroidal anti-inflammatory drug-induced AE, angiotensin converting enzyme inhibitor-induced AE), idiopathic and a recently described form, HAE type 3. These various forms of AE have overlapping symptoms, but some unique clinical and historical features as well as presence of accompanying urticaria can aid in the differential diagnosis. The key to successful management is to rule out conditions that masquerade as AE, detection and avoidance of triggers, early recognition of attacks, and aggressive airway management when warranted. In this article, common and rare forms as well as clinical symptoms, differential diagnosis, and treatment approaches for AE are reviewed. (Turkderm 2013; 47: 7-18

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Cheilitis glandularis: A clinicopathological study in 22 patients

Cited by 42 publications

References 15 publications

Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases

Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases

Oral Potentially Malignant Disorders: An Overview of More than 20 Entities

Angioedema: Diagnosis and treatment approaches

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