Shrimp farmers using inland low‐salinity waters in west Alabama have traditionally used agricultural fertilizers (K‐Mag®, muriate of potash) to raise pond water levels of potassium (K) and magnesium (Mg) to improve the rearing medium for Litopenaeus vannamei. Laboratory and farm trials were performed to investigate the potential of using dietary supplementation of Mg instead of costly agricultural fertilizers. A 5‐wk laboratory trial was devised to test four diets with varying levels of Mg supplementation (0, 0.15, 0.30, and 0.60% Mg chelate) using a magnesium chelate (MgC)–amino acid complex. Juvenile shrimp were stocked into artificial low‐salinity water (5 ppt) designed to contain low levels of Mg. A farm trial was also conducted to test the same diets under field conditions. Although both laboratory and on‐farm trials revealed a trend for increased growth using the diet with the highest Mg supplement, results were not significantly different. The use of magnesium chelates as dietary supplements at levels higher than the requirement level to enhance survival, growth, and osmoregulatory capacity of shrimp reared in inland low‐salinity well waters appeared to have limited potential. Until effective specialized diet formulations are produced, farmers should continue to supplement pond waters with fertilizers containing K and Mg.