Chemical and biological investigation of the marine bacterium Rhodococcus sp. UA13

Next-generation sequencing-based Actinobacteria community associated with Callyspongia sp. from Kepulauan Seribu Marine National Park, Jakarta, Indonesia

“…The factors involved in controlling the expression of these smBGCs are likely to be quite diverse, given the large degree of variability in the habitats and potential hosts, and how they are presumably influencing the secondary metabolite biosynthetic potential of Streptomyces symbionts (Adnani et al 2017). Moreover, secondary metabolites from marine actinomycetes usually show distinct and often complex chemical structures, which help the development of further therapeutic agents efficiently (Elsayed et al 2021). Molecular-based culture methods by adding nutrient supplements that mimic the marine conditions in nutrients content, oxygen gradient, pH, etc.…”