In view of the low efficiency of traditional electrostatic precipitators in removing fine particles, acoustic and pulsed corona discharge coupling fields were proposed to increase particle size. In this paper, monodisperse particles with three different sizes (0.5 μm, 2 μm, and 4 μm) were generated to investigate the agglomeration effect under different parameters in external fields. A larger reduction ratio of particle number concentration resulted in a higher agglomeration efficiency. Results indicated that, in the range from 800 to 2400 Hz, the acoustic agglomeration effect on 4-μm particles was better than that on 0.5-μm and 2-μm particles. In the pulsed corona discharge field, agglomeration efficiencies of the three particle sizes were lower than those in the acoustic field. However, application of the coupling field highly improved agglomeration efficiency compared with the single field. When a pulse input voltage of 50 kV with acoustic sound pressure level (SPL) of 143 dB and frequency of 1600 Hz was selected, the corresponding number reduction ratio of 0.5-μm, 2-μm, and 4-μm particles increased to 0.464, 0.526, and 0.918 from 0.254, 0.438, and 0.814 in the acoustic wave field and 0.226, 0.385, and 0.794 in the pulsed corona discharge field.