Chemical Characterization of the Flavonoid Constituents of Cuscuta reflexa

Chatterjee, Dandopani; Sahu, Ram Kumar

doi:10.20510/ukjpb/2/i3/91163

Cited by 12 publications

(4 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The nine distinct portions were gathered and dried. The portion F1 and F2 were containing waxy material; the parts F3, F4 and F7 were powder however amount was almost no (Chatterjee, 2014). The yield of part F5, F6, F8 and F9 were 210 mg, 170 mg, 380 mg and 280 mg, individually.…”

Section: Methodsmentioning

confidence: 93%

Evaluation of Hepatoprotective and Antioxidant Activity of Isolated Flavonoids Compounds from Ougeinia oojeinensis extracts

Yadav¹,

Dubey²,

Manigauha³

2019

JCHPS

View full text Add to dashboard Cite

The flavonoids present in plant grant different kinds of pharmacological action. It has been reported that the flavonoids assume boss job in assurance of harm liver. Subsequently we wanted to research the hepatoprotective and cancer prevention agent action of segregated flavonoids mixes from Ougeinia oojeinensis leaves extracts. The oil ether, ethanol and watery extracts were set up from leaves of Ougeinia oojeinensis, and screened for phytochemical investigation. The diverse flavonoid compound disengaged from ethanol separate, and further assessed their hepatoprotective and cancer prevention agent movement in CCl4 prompted hepatotoxicity. The most extreme phytoconstituents alongside flavonoids were seen in ethanol extract of leaves of Ougeinia oojeinensis. The nine distinct divisions were isolated and dried from ethanol extracts of Ougeinia oojeinensis. The F8 and F9 demonstrate the nearness of flavonoids, tannins and phenolic mixes. The F8 and F9 indicates intense hepatoprotective action by essentially diminishing the CCl4 prompted modification in SGOT, SGPT, ALP, ACP, all out bilirubin and direct bilirubin in blood. The cancer prevention agent movement of F8 and F9 affirmed on altogether expanding in dimension of catalase, glutathione peroxidase, superoxide dismutase compound, while lipid peroxidation was diminished, when contrasted with CCl4 condition. The consequence of study recommends that the flavonoid compound F9 of Ougeinia oojeinensis showed most extreme hepatoprotective and cell reinforcement action thought about F8.

show abstract

Section: Methodsmentioning

confidence: 93%

Evaluation of Hepatoprotective and Antioxidant Activity of Isolated Flavonoids Compounds from Ougeinia oojeinensis extracts

Yadav¹,

Dubey²,

Manigauha³

2019

JCHPS

View full text Add to dashboard Cite

show abstract

“…The three fractions were further analyzed for phytochemical screening to determine the nature of the isolated compound. [13] Pharmacological Activity…”

Section: Isolation Of Compound From Ethanol Extractsmentioning

confidence: 99%

Untitled

Manigauha¹

2018

IJGP

View full text Add to dashboard Cite

Background: Alangium salvifolium is content of flavonoids and mainly used for management of diabetes in India. In the present study, we evaluated the antioxidant and antidiabetic activity of isolated flavonoids from A. salvifolium leaves extracts in experimental animals. Materials and Methods: The petroleum ether, ethanol and aqueous extracts of leaves of A. salvifolium were prepared by successive Soxhlet extraction process, and further phytochemical screening and in vitro antioxidant were performed. The most effective ethanol extracts of A. salvifolium were selected for separation of flavonoids compound, and consequently qualitative phytochemical analysis was done. The flavonoid containing fractions were screened for antidiabetic activity in streptozotocin (STZ) induced diabetic rats. Results: The ethanol and aqueous extracts of A. salvifolium contain the maximum number of phytoconstituents such as alkaloids, glycosides, carbohydrates, flavonoids, tannins, and polyphenol. The findings of in vitro antioxidant activity confirmed that ethanol extracts expressed higher antioxidant activity compared to aqueous extract, and hence ethanol extracts were further selected for the isolation of various fractions. The FAS6 to FAS7 indicate the presence of phenolic compounds and flavonoids. The FAS6 and FAS7 significantly reduced the blood glucose level, total cholesterol, low-density lipoprotein, triglycerides and a significant rise in high-density lipoprotein in STZ-induceddiabetic rats as compared to the diabetic control group. Conclusion: Based on the results of the antidiabetic activity of FAS6 to FAS7 isolated from leaves of A. salvifolium were due to its antioxidant property.

show abstract

“…Elutes collected were monitored by thin layer chromatography (eluent: DCM-MeOH, 9:1 and 3:2) for homogeneity and the similar fraction were pooled together. The eight different fractions were collected and dried [13]. The phytochemical screening was performed according to Harborne [14] and Kokate [15].…”

Section: Isolation Of Compound From Hydroalcoholic Extractsmentioning

confidence: 99%

Anti-inflammatory and Anti-arthritis Activity of Flavonoids Fractions Isolated from Centipeda minima Leaves Extracts in Rats

Sarkar¹,

Tripathi²,

Sahu³

2017

Clin Exp Pharmacol

View full text Add to dashboard Cite

Centipeda minima has been used since centuries as a traditional medicinal plant in treating a number of disease conditions, the bioactive components responsible for its anti-inflammatory and anti-arthritis activity have not been identified. The present study was planned to isolate flavonoids fractions from Centipeda minima leaves extracts, and assessed anti-inflammatory and anti-arthritis activity in rats. The hydroalcoholic and aqueous extracts of Centipeda minima leaves were prepared and evaluated for in vitro antioxidant activity namely DPPH, total polyphenol content, total flavonol content and reducing power assay. The different fractions were isolated from hydroalcoholic extracts by using column chromatography. The Flavonoids fractions were investigated for anti-inflammatory and anti-arthritis activity in carrageenan rat induced paw oedema, cotton pellet-induced granuloma model and adjuvant induced chronic arthritis in rats. The findings of in vitro antioxidant activity confirmed that hydroalcoholic extracts expressed higher antioxidant activity compared to aqueous extract, and hence hydroalcoholic extracts was further selected for the isolation of various fractions. The results of phytochemical study suggest that FCM6, FCM7 and FCM8 exposed the presence of polyphenol and flavonoids. The fraction FCM6, FCM7 and FCM8 (25 mg/kg) exhibits significant antiinflammatory and anti-arthritis activity. The outcomes suggest that the anti-inflammatory and anti-arthritis activity of isolated fraction was due to presence of flavonoids and polyphenols.

show abstract

Chemical Characterization of the Flavonoid Constituents of Cuscuta reflexa

Cited by 12 publications

References 7 publications

Evaluation of Hepatoprotective and Antioxidant Activity of Isolated Flavonoids Compounds from Ougeinia oojeinensis extracts

Evaluation of Hepatoprotective and Antioxidant Activity of Isolated Flavonoids Compounds from Ougeinia oojeinensis extracts

Untitled

Anti-inflammatory and Anti-arthritis Activity of Flavonoids Fractions Isolated from Centipeda minima Leaves Extracts in Rats

Contact Info

Product

Resources

About