Chemical, Clinical, and Immunological Studies on the Products of Human Plasma Fractionation. Xvi. Fibrin Clots, Fibrin Films, and Fibrinogen Plastics 12

Chemical, Clinical, and Immunological Studies on the Products of Human Plasma Fractionation. I. The Characterization of the Protein Fractions of Human Plasma 12

“…Of these, fibrinogen, separated in Fraction I, may be considered the most important since its molecular properties determine to a large extent the mechanical properties of the clot (21). The conversion of a fibrinogen solution into the fibrin clot is brought about by the interaction of fibrinogen and thrombin.…”

Chemical, Clinical, and Immunological Studies on the Products of Human Plasma Fractionation. Xxii. Fibrin Films in Neurosurgery, With Special Reference to Their Use in the Repair of Dural Defects and in the Prevention of Meningocerebral Adhesions 12

“…The films used in the patients reported in this paper have all been of the type which has been described by Ferry and MNIorrison (1). This is a tough and rubbery filml which seeims to possess the physical properties desirable in a dural substitute.…”

“…Experimental and clinical data are presented which suggest strongly that the best solution to date for these and related neurosurgical problems is offered by the fibrin films prepared by Ferry and Morrison (1,2) from the products of large scale plasma fractionation (3,4). ANIMAL …”

Chemical, Clinical, and Immunological Studies on the Products of Human Plasma Fractionation. Xix. A Note on the Use of Fibrinogen and Thrombin in the Surface Treatment of Burns 123

“…Of these the following types (6) Preliminary trials of certain of these films have been made on a small group of burns at the Boston City Hospital.7 These cases are presented in Table I. There are included both second and third degree burns of arms, legs, and trunk.…”