2002
DOI: 10.1002/ffj.1084
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Chemical composition and antimicrobial activity of the essential oil and CO2 extracts of the oriental tobacco, Prilep

Abstract: A study of the chemical composition of essential oil and CO 2 extracts of the middle and upper leaf positions of the oriental tobacco Prilep was performed using GC and GC-MS. The major constituents were: in the essential oil, neophytadiene and solanone; in CO 2 extract I, neophytadiene; and in CO 2 extract II, nicotine, nonacosane and solanesol. The antimicrobial activity of the essential oil and CO 2 extracts were investigated against the microorganisms: Escherichia coli, Staphylococcus aureus and Pseudomonas… Show more

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Cited by 51 publications
(33 citation statements)
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“…indices; Exp = retention indices determined relative to a homologous series of n-alkanes (C 7 -C 30 ) on a DB-5MS column, Lit = literature RI values [1,10,[12][13][14][15][16][17][18][19][20][21][22][23][24][25][26]. syn.…”
mentioning
confidence: 99%
“…indices; Exp = retention indices determined relative to a homologous series of n-alkanes (C 7 -C 30 ) on a DB-5MS column, Lit = literature RI values [1,10,[12][13][14][15][16][17][18][19][20][21][22][23][24][25][26]. syn.…”
mentioning
confidence: 99%
“…Neophytadiene is a branched, unsaturated hydrocarbon found in plants such as tobacco and marigold, and algae, which has antimicrobial activity (Mendiola et al 2008;Palic et al 2002;Plaza et al 2010). In the study, the concentrations of neophytadiene in the treated plants were higher than in the control plants, suggesting that neophytadiene may be involved in the response mechanism of E. cordifolius to EGs.…”
Section: Discussionmentioning
confidence: 66%
“…These compounds are reported to have anti putrefying and antimicrobial effects. (16,22,23). Nettle have other constituents which plays major role in antibacterial effect such as alkaloids, phenols, flavonoids, tannins and saponins in these plants extract which have been claimed to be responsible for their antimicrobial activity (7,14).Alkaloid, it is antibacterial activity may be due to its ability to react with amino, carboxyl, sulfhydryl and hydroxyl groups in bacterial protein as well as nucleic acids, it highly reactive chemical compounds that combine with proteins to give intermolecular cross-links and intercalate with DNA (15).Tanninic substances are another constituents which are capable of precipitating gelatin from solution, a property is known as astringency.…”
Section: Discussionmentioning
confidence: 99%
“…Nettle have other constituents which plays major role in antibacterial effect such as alkaloids, phenols, flavonoids, tannins and saponins in these plants extract which have been claimed to be responsible for their antimicrobial activity (7,14).Alkaloid, it is antibacterial activity may be due to its ability to react with amino, carboxyl, sulfhydryl and hydroxyl groups in bacterial protein as well as nucleic acids, it highly reactive chemical compounds that combine with proteins to give intermolecular cross-links and intercalate with DNA (15).Tanninic substances are another constituents which are capable of precipitating gelatin from solution, a property is known as astringency. It has been reported to prevent the development of microorganisms by precipitating microbial protein and making nutritional proteins unavailable for them (9,16).Phenolic compound is mostly hydrophobic, it has a hydroxyl group (-OH). The importance of this group on antimicrobial activity is well known, the site(s) and number of hydroxyl groups on the phenol group are thought to be related to their relative activity to microorganisms (17,18).The high activity of the phenolic components may be further explained in terms of the alkyl substitution into the phenolic nucleus, which is known to enhance the antimicrobial activity of phenols.…”
Section: Discussionmentioning
confidence: 99%