Chemical composition, anti-dermatophytic activity, antioxidant and total phenolic content within the leaves essential oil of Vitex trifolia

Abstract

This study was carried out to determine the contents of total phenol as well as antioxidant activity, the chemical composition and anti-dermatophytic activity of the Vitex trifolia (Family: Lamiaceae) essential oil of the leaves. Hydro-distillation of the V. trifolia was carried out using Clavenger Vendor to obtain the volatile oil. Total phenolic content and antioxidant activity were determined using the Folin-Ciocalteau reagent and DPPH radical scavenging assay test by spectrophotometric methods. Gas chromatographymass spectrometric (GC-MS) analyses (BP-1 chrompack capillary column) of the essential oil was performed and its composition determined. The in-vitro anti-dermatophytic activity was evaluated both by agar diffusion and microbroth dilution methods against Candida albicans ATCC 90029, C. albicans

A Comparative Study of Essential Oil Constituents and Phenolic Compounds of Arabian Lilac (Vitex Trifolia var. Purpurea): An Evidence of Season Effects

“…The Vitex genus (Verbenaceae family) comprises nearly 270 species predominantly of trees and shrubs that are widely distributed in tropical and subtropical regions, along with some species growing in the temperate zones [1]. Many species of this genus have been extensively commended because of notable therapeutic effects on several female disorders such as endometriosis, abnormal menstrual cycle, menopausal conditions, corpus luteum insufficiency, hyper-prolactinaemia, infertility, acne, menopause, disrupted lactation, and cyclic breast pain, and, therefore, Vitex genus has been known as female herb since ancient times [2].…”

“…This plant can be easily distinguished from other plants of this species due to the annual color variation of leaves from green to violet and, therefore, it is mainly used as an ornamental plant in the landscapes. Leaves are traditionally recommended for the treatment of rheumatic pains, inflammation, sprains, and wound healing [1]. Infusion and decoction are also beneficial therapeutic preparations in the improvement of intestinal ailments and treatment of tuberculosis and amenorrhea and have been used by indigenous populations.…”

“…Infusion and decoction are also beneficial therapeutic preparations in the improvement of intestinal ailments and treatment of tuberculosis and amenorrhea and have been used by indigenous populations. Moreover, the essential oil (EO) of Vitex trifolia L. is often used as a sedative, an anti-inflammatory and used for headaches, colds and coughs as well as in liver disorders and HIV [1,7]. Phytochemical studies revealed that the methanolic extract of leaves possesses strong antioxidant activity and is considered as a potent anticancer agent due to its high content of phenolic compounds including phenolic acids, flavonoids, flavones, and flavonols [5].…”

Essential oils from Vitex trifolia as an effective repellent for Aedes aegypti

“…The main constituents of the essential oils from V. trifolia are monoterpenes and sesquiterpenes, namely 1R-αpinene, ocimene, 3-carene, toluene, p-ethyl-, eucalyptol, and 3-methoxy-5-methylphenol (Devi and Singh 2014). In another study, caryophyllene and eucalyptol are the main constituents of the oil V. trifolia, which account for 38% and 26% respectively (Thomas et al 2019).…”

Natural Products and Nutrients against Different Viral Diseases: Prospects in Prevention and Treatment of SARS-CoV-2

“…Fruits of the plants contain essential oils, monoterpenes, diterpenes, beta-sitosterol [ 62 , 63 , 64 , 65 , 66 , 67 , 68 ]. The leaves and bark of the plant contain essential oils, flavones, and artemetin [ 65 ].…”