Chemical composition, antibacterial, antifungal and antioxidant activities of Algerian Eryngium tricuspidatum L. essential oil

Abstract

This study describes the chemical composition and the antibacterial, antifungal and antioxidant activities of the essential oil extracted from aerial parts of the Algerian Eryngium tricuspidatum L., obtained by hydrodistillation and analysed by using the combination of gas chromatography (GC) and GC/mass spectrometry. A total of 63 compounds were identified accounting for 93.1% of the total oil. Chemical composition of oil was characterised by a high proportion of oxygenated sesquiterpenes (49.6%) among which α-bisabolol (32.6%) was the predominant compound. The sesquiterpene hydrocarbons represent the second major fraction (31.9%) with α-curcumene (6.5%) being the predominant one. Antibacterial and antifungal activities of the oil were tested using the micro-well determination of minimum inhibitory concentration (MIC) assay against eleven bacteria and two Candida species. It was found that the aerial parts of E. tricuspidatum exhibited interesting antibacterial and anticandidal activities (MIC = 9 μg/mL against several strains of bacteria and MIC = 4.6 μg/mL against Candida albicans). The antioxidant effect of this oil was evaluated using the 2,2-diphenyl-l-1-picrylhydrazil (DPPH) and ferric reducing antioxidant power (FRAP) assays. Results revealed significant activities (DPPH method: IC₅₀ = 510 μg/mL; FRAP assay: reducing power of oil increases from 0.0188 at 5 μg/mL to 0.5016 at 1000 μg/mL).

Cytotoxic Essential Oils from Eryngium campestre and Eryngium amethystinum (Apiaceae) Growing in Central Italy

“…On the other hand, the two essential oils seemed to act as moderate reducing agents (FRAP activity). As an example, a minor DPPH radical scavenging activity and FRAP reducing power has been reported for essential oil from Algerian E. tricuspidatum L. [61] With regard to the main components found in the two essential oils investigated, low antioxidant activity has been reported for germacrene D, the major component in both oils. [59] A work reported the in vitro antioxidant activity of root extracts of E. campestre.…”

Chemical Composition and Antimicrobial Activity of the Essential Oil from Aerial Parts and Roots of Eryngium barrelieri Boiss. and Eryngium glomeratum Lam. from Tunisia

“…To our knowledge, the predominance of terpene alcohols or oxides is more unusual within this genus ( e.g . ). As for essential oils of E .…”

“…The essential oils extracted from this genus so far have exhibited wide variability in their major compounds, the most commonly encountered ones being sesquiterpenes such as α ‐bisabolol, α ‐muurolene and germacrene D; and non‐terpenic oxygenated compounds such as trimethylbenzaldehyde and ( E )‐2‐dodecenal…”

“…Previous studies have shown various positive biological effects of essential oils within this genus, essentially antibacterial and antifungal activities. E. tricuspidatum exhibited interesting antibacterial and anticandidal activities with minimum inhibitory concentration ( MIC ) values ranging from 4.6 to 74 μg/ml . Other works related to antibacterial activities of essential oils relying only on measurement of inhibition diameter by disc diffusion method showed that the essential oil of E. maritimum (5 μl/disc) was found mainly efficient against Escherichia coli strains with an inhibition zone of 20 mm of diameter .…”

Mystroxylon aethiopicum chloroform root bark extracts phytochemical analysis using gas chromatography mass spectrometry

“…Compounds that have been reported to exhibit antibacterial and antifungal activities are δ-cadinol, copaene, caryophyllene, α-calacorene, β-eudesmol, γ-cadinene, aromadendrene, thujopsene, α-cubebene, cyperene, α-curcumene, caryophyllene oxide, norelidol, farnesol, geranyl linalool, totarol, geranylgeraniol and borneol (Ho et al, 2011;Kubo et al, 1992;Pérez et al, 2011;Vukovic et al, 2008;Baskaran et al, 2016;Sarada et al, 2011;Rajeswari et al, 2011;Su and Ho, 2013;Solis et al, 2004;Krist et al, 2015;Sadashiva et al, 2010;Merghache et al, 2014;Manter and Kelsey, 2007;Barrero et al, 2005;Naidoo et al, 2009;Shaik et al, 2014;Mulyaningsih et al, 2010;Ghannadi et al, 2012). α-muurolene, isolongifolene, α-cubebene and (Z,Z)-α-farnesene have been reported to possess antioxidant activities (Gurbuz et al, 2013;Naidoo et al, 2009;Çelik, 2014;Rangasamy and Namasivayam, 2014).…”