Chemical composition, antioxidant, and antimicrobial activity of Elsholtzia beddomei C. B. Clarke ex Hook. f. essential oil

Sripahco, Teerapong; Khruengsai, Sarunpron; Charoensup, Rawiwan; Tovaranonte, Jantrararuk; Pripdeevech, Patcharee

doi:10.1038/s41598-022-06358-6

Cited by 18 publications

(4 citation statements)

References 27 publications

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“…26 and also act as antifungal agent against several fungal strains. 27 Similar findings were observed in the work of Sripahco et al 28 with essential oils obtained from E. splendens which showed antibacterial inhibitory activity against S. aureus, S. epidermidis, and Propionibacterium acnes. Besides, antimicrobial activity appeared to be a result of the synergistic effect of the mixture of bioactive compounds present in the volatile oil.…”

Section: Resultssupporting

confidence: 73%

GC-MS Analysis and Antimicrobial Evaluation of Essential Oil from the Epicarp of Nigerian Grown Afraegle paniculata (Rutaceae)

Babatunde

Ajayi

et al. 2023

Dhaka Univ. J. Pharm. Sci

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Essential oils are used as therapeutic agents in aromatherapy. In this study, the chemical composition and antimicrobial activity of the essential oils from the epicarp of Afraegle paniculata fruits from Nigeria were evaluated. The essential oil was obtained via hydro distillation and chemical components of the oils were analysed on Agilent Technologies 7890A gas chromatograph-mass spectrometry system. Antimicrobial assay was performed by disc diffusion method. GC-MS analysis revealed sixteen compounds consisting mainly of oxygenated monoterpene (39.61 %), esters (15.3 %), sesquiterpenes (13.1 %) and sesquiterpene alcohol (9.42 %). The oil showed appreciable activity against all the tested microorganisms except Aspergillus niger. At concentration of 1000 μg/ml, the inhibitory effect observed for S. aureus was 16 mm followed by 15 mm for B. subtilis and 7 mm for P. aeruginosa. The findings suggest that essential oil from A. paniculata fruits could serve as a valuable raw material for perfumery and cosmetic products. Dhaka Univ. J. Pharm. Sci. 22(1): 73-80, 2023 (June)

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Section: Resultssupporting

confidence: 73%

GC-MS Analysis and Antimicrobial Evaluation of Essential Oil from the Epicarp of Nigerian Grown Afraegle paniculata (Rutaceae)

Babatunde

Ajayi

et al. 2023

Dhaka Univ. J. Pharm. Sci

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“…The antioxidant of L. nervosa EO against an ABTS (2,2 -Azinobis-(3-ethylbenzothiazolin-6-sulfonic acid) diammonium salt) radical was investigated using the following method: the ABTS radical cation reagent was prepared by mixing 7 mM ABTS solution with 2.6 mM potassium persulfate, which was subsequently kept in the dark at room temperature for at least 12 h [25]. The ethanolic EO solution was prepared according to the following gradients: 25, 10, 5, 2.5, 1, and 0.5 mg mL −1 .…”

Section: Abts Methodsmentioning

confidence: 99%

Chemical Composition, In Vitro Antioxidant Activities, and Inhibitory Effects of the Acetylcholinesterase of Liparis nervosa (Thunb.) Lindl. Essential Oil

Zhao

Gao

et al. 2023

Biomolecules

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The present study aimed to investigate the essential oil composition of Liparis nervosa (Thunb.) Lindl., grown in China, and to determine its antioxidant and inhibitory effects on acetylcholinesterase. The essential oil was obtained by hydrodistillation, and the chemical compounds were analyzed by GC-MS and GC-FID. We used 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric reducing assay power (FRAP) to evaluate the antioxidant activity. The anti-acetylcholinesterase activity of the essential oil was also examined. Sixty-seven compounds were identified, representing 98.50 % of the total essential oil, which was shown to be rich in methyl (9E,11E)-octadeca-9,11-dienoate (31.69%), n-hexadecanoic acid (15.08%), isopropyl palmitate (12.44%), propyl tetradecanoate (7.20%), tetradecanoic acid (4.01%), 17-octadecynoic acid (3.71%), and pentacosane (2.24%). Its antioxidant ability was analyzed via ABTS (IC50 = 721.95 ± 9.93 μg/mL), DPPH scavenging capacity (IC50 > 10,000 μg/mL), and the FRAP method (Trolox equivalent antioxidant concentration 39.64 ± 3.38 μM/g). Acetylcholinesterase inhibition effects were evaluated and had an IC50 value of 51.96 ± 14.26 μg/mL. The results show that this essential oil has interesting biological potential, encouraging further investigations, especially regarding the mechanisms of action of its antioxidant and anti-acetylcholinesterase activity. This is the first time that the chemical composition, antioxidant activity, and acetylcholinesterase inhibition effects of essential oil from L. nervosa have been studied.

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“…Plants are an extensive source of natural products [13] with broad pharmacological potential [14]. Over millions of years, plant secondary metabolites have evolved and acquired a unique chemical diversity, which subsequently led to a variety of biological activities and drug-like properties [15].…”

Section: Introductionmentioning

confidence: 99%

Quality, Safety and Biological Studies on Campylanthus glaber Aerial Parts

Lima,

Malmir,

Camões

et al. 2023

Pharmaceuticals

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In Cabo Verde, several endemic species are used in traditional medicine. However, no scientific studies have been conducted on the quality, efficacy, and safety of most of these plants. This study focused on establishing the botanical and chemical identification parameters required for a quality monograph of Campylanthus glaber Benth. aerial parts, a medicinal plant of Cabo Verde traditionally used to treat fever and muscular pain. In addition, in vitro antioxidant and antihyperglycemic activity, cytotoxicity, and genotoxicity were assessed for this medicinal plant. Optical microscopy, LC/UV-DAD-ESI/MS, and colorimetric assays were used for botanical, chemical, and biological studies, respectively. Cytotoxicity was assessed by the MTT assay with HepG2 cells, and genotoxicity by the Ames test. Microscopically, the xeromorphic leaf of C. glaber presents a thick cuticle (13.6–25.5 µm), thick-walled epidermal cells, anomocytic-type stomata, glandular trichomes (stalk length = 49.4–120.8 µm), and idioblasts containing calcium oxalate microcrystals. The chemical screening of aqueous and hydroethanolic extracts of this medicinal plant revealed the presence of organic acids, iridoids, phenylethanoids, and flavonoids as the main classes of marker compounds, with malic acid, citric acid, and verbascoside being the main marker compounds identified. Both extracts showed similar LC/UV-DAD/ESI-MS qualitative profiles and DPPH radical scavenger activity (IC50 = 130.9 ± 1.4; 134.3 ± 3.1 µg/mL). The hydroethanolic extract inhibited both α-amylase and α-glucosidase enzymes in a dose-dependent manner. Both extracts showed no cytotoxicity (up to 1000 µg/mL) by the MTT assay and no genotoxic potential with or without metabolic activation up to 5 mg /plate. The results obtained are an important contribution to the monographic quality assessment of C. glaber aerial parts and suggest that this medicinal plant may be safe and potentially used as an herbal drug raw material for pharmaceutical purposes.

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Chemical composition, antioxidant, and antimicrobial activity of Elsholtzia beddomei C. B. Clarke ex Hook. f. essential oil

Cited by 18 publications

References 27 publications

GC-MS Analysis and Antimicrobial Evaluation of Essential Oil from the Epicarp of Nigerian Grown Afraegle paniculata (Rutaceae)

GC-MS Analysis and Antimicrobial Evaluation of Essential Oil from the Epicarp of Nigerian Grown Afraegle paniculata (Rutaceae)

Chemical Composition, In Vitro Antioxidant Activities, and Inhibitory Effects of the Acetylcholinesterase of Liparis nervosa (Thunb.) Lindl. Essential Oil

Quality, Safety and Biological Studies on Campylanthus glaber Aerial Parts

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