Chemical Composition, Antioxidative and Anticancer Activities of the Essential Oil: Curcumae Rhizoma–Sparganii Rhizoma,  a Traditional Herb Pair

Xu, Guanling; Geng, Di; Xie, Meng; Teng, Kai-Yue; Tian, Yuxin; Liu, Zizhen; Chen, Yan; Wang, Yan; Zhang, Xia; Song, Yan; Yang, Yue; She, Gaimei

doi:10.3390/molecules200915781

Cited by 37 publications

(26 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…wenyujin (5.10 μg/ml) reveal much better antioxidative activities than commercial antioxidant ascorbic acid (6.50 μg/ml). It has been demonstrated that curdione, neocurdione, aromadendreneoxide , ar ‐curcumene, β ‐santalol, β ‐sesquiphellandrene, camphor, curzerene, zerumbone, and zingiberene are the major constituents in Curcuma essential oils with superior antioxidant activity …”

Section: Resultsmentioning

confidence: 99%

Variation on Composition and Bioactivity of Essential Oils of Four Common Curcuma Herbs

Zhang

Yang

Chen

et al. 2017

Chemistry & Biodiversity

View full text Add to dashboard Cite

Chemical compositions, antioxidative, antimicrobial, anti-inflammatory, and cytotoxic activities of essential oils extracted from four common Curcuma species (Curcuma longa, Curcuma phaeocaulis, Curcuma wenyujin, and Curcuma kwangsiensis) rhizomes in P. R. China are comparatively studied. In total, 47, 49, 35, and 30 compounds are identified in C. longa, C. phaeocaulis, C. wenyujin, and C. kwangsiensis essential oils by GC/MS, and their richest compounds are ar-turmerone (21.67%), elemenone (19.41%), curdione (40.23%) and (36.47%), respectively. Moreover, C. kwangsiensis essential oils display the strongest DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavenging activity (IC , 3.47 μg/ml), much higher than ascorbic acid (6.50 μg/ml). C. phaeocaulis oils show the best antibacterial activities against Escherichia coli (MIC, 235.54 μg/ml), Pseudomonas aeruginosa (391.31 μg/ml) and Staphylococcus aureus (378.36 μg/ml), while C. wenyujin and C. kwangsiensis oils show optimum activities against Candida albicans (208.61 μg/ml) and Saccharomyces cerevisiae (193.27 μg/ml), respectively. C. phaeocaulis (IC , 4.63 μg/ml) and C. longa essential oils (73.05 μg/ml) have the best cytotoxicity against LNCaP and HepG2, respectively. C. kwangsiensis oils also exhibit the strongest anti-inflammatory activities by remarkably down-regulating expression of COX-2 and TNF-α. Therefore, due to their different chemical compositions and bioactivities, traditional Chinese Curcuma herbs should be differentially served as natural additives for food, pharmaceutical, and cosmetic.

show abstract

Section: Resultsmentioning

confidence: 99%

Variation on Composition and Bioactivity of Essential Oils of Four Common Curcuma Herbs

Zhang

Yang

Chen

et al. 2017

Chemistry & Biodiversity

View full text Add to dashboard Cite

show abstract

“…This anticancer activity may be due to the active constituents present in the essential oil [13], such as Limonene that show cytotoxicity against breast carcinoma [23], and Mayurone that has anticancer against (MCF-7) cells [24], Borneol that exhibit cytotoxic activity against (HepG2, Caco-2 and VH10) cell lines [25], Bisabolene that demonstrate cytotoxic activity against breast cancer [26], Cymene that has cytotoxic activity against (HepG2, K562, and B16-F10) cell lines [27], Camphor that appear cytotoxic activity against MRC-5, HT-29 and HCT 116 cell lines [28].…”

Section: Resultsmentioning

confidence: 99%

The Evaluation of Antimicrobial and Cytotoxic Activity of the Essential Oil Extracted From the Aerial Parts of Southernwood Herb (Artemisia Abrotanum L.) That Recently Grown in Iraq

Almahdawy

Said

Abbas

et al. 2017

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: This research is to study the assessment of the antimicrobial and cytotoxic activity of the essential oil extracted from the aerial parts of Artemisia abrotanum L. that recently grown in Iraq. Methods:The essential oil of A. abrotanum was extracted by hydrodistillation using Clevenger apparatus. This essential oil was tested for antimicrobial activity of five different pathogenic microorganisms (Gram-positive [Staphylococcus aureus and Bacillus subtilis] and Gram-negative [Salmonella typhi and Escherichia coli] bacterial strains) and fungi: Candida albicans using diffusion well agar method. Furthermore, this essential oil was tested for cytotoxic activity using rhabdomyosarcoma cell line, and the growth or inhibition of cancer cells was measured by MTT method. Results:The obtained results show that the antibacterial activity for A. abrotanum against S. aureus was at concentrations 40, 25, and15 µl with minimum inhibitory concentrations of 20 mm, while it showed antibacterial activity against E. coli for four different concentrations of 40, 25, 15, and10 μl with inhibition zone of 16, 12, 14, and 10 mm, respectively, and it showed antifungal activity against C. albicans at four concentrations 40, 25, 15, and10 μl with inhibition zone of 18, 24, 26, and 30 mm, respectively. The cytotoxic activity of the extracted essential oil was showed that the three concentrations of the extract (25, 50, and 100 μg/ml) were all lower significantly as compared to dimethyl sulfoxide group. A significant difference was seen for group 25 with both groups 50 and 100, but no significant difference was seen between the two later. Finally, the antimicrobial and anticancer activity of this plant could be due to its essential oil constituents: Borneol, cymene, camphor, terpineol, eucalyptol, and aromadendrene. Conclusion:The essential oil of A. abrotanum L. has a potent antimicrobial and anticancer effect against the tested microbial organisms and the cancer cells.

show abstract

“…phaeocaulis and S. stoloniferum(Ezhu and Sanleng), as a basic HP was first recorded as Sanleng Wan in "Jingyan Liangfang" during the Qing dynasty. The pairs possess extensive activities, including anticancer activity, antiinflammatory activity, and antithrombotic activity (Xu et al, 2015). This HP has shown therapeutic effects on hysteromyoma via the regulation of multiple metabolic pathways.…”

Section: The Combining Rule and Synergy Effects Of Hps And Prescriptionsmentioning

confidence: 99%

Modular Characteristics and Mechanism of Action of Herbs for Endometriosis Treatment in Chinese Medicine: A Data Mining and Network Pharmacology–Based Identification

Zheng

et al. 2020

Front. Pharmacol.

View full text Add to dashboard Cite

could also regulate VEGF signaling, toll-like reporter signaling, NF-kB signaling, MAPK signaling, PI3K-Akt signaling, and the HIF-1 signaling pathway, among others. Synergies often exist in herb pairs and herbal prescriptions. In conclusion, we identified some important targets, target pairs, and regulatory networks, using bioinformatics and data mining. The combination of data mining and network pharmacology may offer an efficient method for drug discovery and development from herbal medicines.

show abstract

Chemical Composition, Antioxidative and Anticancer Activities of the Essential Oil: Curcumae Rhizoma–Sparganii Rhizoma, a Traditional Herb Pair

Cited by 37 publications

References 32 publications

Variation on Composition and Bioactivity of Essential Oils of Four Common Curcuma Herbs

Variation on Composition and Bioactivity of Essential Oils of Four Common Curcuma Herbs

The Evaluation of Antimicrobial and Cytotoxic Activity of the Essential Oil Extracted From the Aerial Parts of Southernwood Herb (Artemisia Abrotanum L.) That Recently Grown in Iraq

Modular Characteristics and Mechanism of Action of Herbs for Endometriosis Treatment in Chinese Medicine: A Data Mining and Network Pharmacology–Based Identification

Contact Info

Product

Resources

About