Chemical composition of Allium schoenoprasum leaves and inhibitory effect of their extract on tumor growth in mice

Ширшова, Т. И.; Beshlei, I. V.; Deryagina, V. P.; Рыжова, Н. И.; Matistov, N. V.

doi:10.1007/s11094-013-0867-8

Cited by 16 publications

(12 citation statements)

References 5 publications

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“…A. schoenoprasum leaf extract from some studies with different methods reported that these contain bis -(2-sulfhydryethyl)-disulfide, 2,4,5-trithiahexane, tris -(methylthio)-methane [ 63 ], quercetin, kaempferol, myricetin, catechin, rutin, chlorogenic acid, p -coumaric acid, ferulic acid, caffeic acid [ 62 , 65 ], folionin A 1 , folionin A 2 , folionin B [ 66 ], sitosterol, stigmasterol, campesterol, cholesterol, free fatty acid, monoacylglycerin, diacylglycerin, triacylglycerin, linoleic acid, palmitic acid, spirostanols (deltonin, saponin A), furostanols (deltoside, protodioscin) [ 67 ] and I-ketose [ 68 ] ( Figure 4 ).…”

Section: Isolation Methods and Compound Content Of Allium Species Leavesmentioning

confidence: 99%

“…The phosphomolybdenum reduction assay [102] Antimicrobial [103,104]; Anti-inflammatory [88]; Inhibitor pancreatic α-amylase and glucoamylase [53] A. ursinum DPPH radical-scavenging ability [70,71,105]; ferric reducing antioxidant power (FRAP) assay [68]; ABTS radical scavenging assays [23] Antimicrobial [72,105]; Antifungal [21]; Antiplatelet [17] A. schoenoprasum DPPH radical-scavenging ability; ferric reducing antioxidant power (FRAP) assay [68]; DPPH bleaching method; the Trolox equivalent antioxidant capacity (TEAC) assay [64]; the total iron reduction's potential technique [62]; ORAC (oxygen radical absorbance capacity) [65] Anti-inflammatory [73]; Antitumor [67]; Antiplatelet [65] A. fistulosum DPPH free radical scavenging assay [61]; ORAC (oxygen radical absorbance capacity) [65] Anti-inflammatory [87]; Antiplatelet [65] A. scorodoprasum Ferric reducing/antioxidant power (FRAP); DPPH radical scavenging activity assay [12] -A. vineale Ferric thiocyanate method; ferric ions (Fe 3+ ) reducing antioxidant power assay (FRAP); DPPH free radical-scavenging activity [16] Table 1. Cont.…”

Section: A Sativummentioning

confidence: 99%

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Antioxidant Properties and Structure-Antioxidant Activity Relationship of Allium Species Leaves

et al. 2021

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Allium is a genus that is widely consumed and used as traditional medicine in several countries. This genus has two major species, namely cultivated species and wild species. Cultivated species consist of A. cepa L., A. sativum L., A. fistulosum L. and A. schoenoprasum L. and wild species consist of A. ursinum L., A. flavum L., A. scorodoprasum L., A. vineale L. and A. atroviolaceum Boiss. Several studies report that the Allium species contain secondary metabolites such as polyphenols, flavonoids and tannins and have bioactivity such as antioxidants, antibacterial, antifungal, anti-inflammatory, pancreatic α-amylase, glucoamylase enzyme inhibitors and antiplatelets. This review summarizes some information regarding the types of Allium species (ethnobotany and ethnopharmacology), the content of compounds of Allium species leaves with various isolation methods, bioactivities, antioxidant properties and the structure-antioxidant activity relationship (SAR) of Allium compounds.

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Section: Isolation Methods and Compound Content Of Allium Species Leavesmentioning

confidence: 99%

Section: A Sativummentioning

confidence: 99%

Antioxidant Properties and Structure-Antioxidant Activity Relationship of Allium Species Leaves

et al. 2021

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“…The extensive uses of chives ( Allium schoenoprasum ), introduced sage ( Salvia pratensis , L amiaceae ), European elderberry ( Sambucus nigra , Caprifoliaceae ) and common dandelion ( Taraxacum officinale ) range from culinary for flavouring dishes to medical purposes, such as antitussives, antiseptics, antifungals, antispasmodics, and anti-inflammatories, amongst other properties [9,10,11,12]. These pharmaceutical uses are associated with the rich amount of polyphenols which are found in these plants [13,14]. It is well established that polyphenols have antitumoral properties by virtue of their antioxidant activities, which have been studied for many years [15,16,17,18].…”

Section: Introductionmentioning

confidence: 99%

Polyphenolic Extracts of Edible Flowers Incorporated onto Atelocollagen Matrices and Their Effect on Cell Viability

et al. 2013

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Abstract:The phenolic extract of chives flowers (Allium schoenoprasum, Liliaceae), introduced Sage (Salvia pratensis, Lamiaceae), European elderberry (Sambucus nigra, Caprifoliaceae) and common dandelion (Taraxacum officinale, Asteraceae) were characterised by High Performance Liquid Chromatography and incorporated in different concentrations onto atelocollagen thin films. In order to assess the biological impact of these phenolic compounds on cell viability, human immortalised non-tumorigenic keratinocyte cell line was seeded on the thin films and cell proliferation was determined by using an MTT assay. In addition, their antimicrobial activity was estimated by using an agar diffusion test. Data indicated the concomitance between cell viability and concentration of polyphenols. These findings suggest that these phenolic-endowed atelocollagen films might be suitable for tissue engineering applications, on account of the combined activity of polyphenols and collagen.

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“…The diallyl sul de content in the chive oil inhibits a wide spectrum of foodborne pathogens, while the phenolic compounds, steroidal saponins, exhibited antiproliferative effects [4,5]. Extracts from the chive leaves could inhibit Ehrlich carcinoma, and attenuates erythrocyte deformability in sickle cell anemia patients [6,7]. However, it was also found that cadmium and selenium could accumulate in this plant to a toxic level [8][9][10].Thus, study on the extracts from Allium schoenoprasum, which could e ciently eliminate the heavy metal while maintains its biological function, became signi cant.…”

Section: Introductionmentioning

confidence: 99%

Purification, Characterization, and Self-Assembly of the Polysaccharides from Allium Schoenoprasum

Zhang

Zheng

et al. 2020

Preprint

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Abstract Background: Allium schoenoprasum is a world-wide common vegetable while only its leave is used in the food factory. Its stalk is largely discarded, for potential heavy metal accumulations, which eventually lead to an environmental contamination. To fully utilize this vegetable and minimize its metal content, the major polysaccharide content is purified and characterized with chemical and computational approaches.Results: The major polysaccharide component from the stalk of Allium schoenoprasum (AssP) was extracted and purified. The gel filtration chromatography purified AssP exhibited a molecular weight of around 1.6 kDa, which was verified by MALDI-ToF-MS. Monosaccharide analysis revealed its composition as rhamnose: arabinose: galactose: glucose: mannose: fructose with a molar ratio of 0.0264:2.46:3.71:3.35:1.00:9.93, respectively. Multiple NMR analysis revealed its backbone as α-Ara/Glu/Gal-(1→2)-linked and β-D-Fru-(4→5)-linked sugar residues. There was no tertiary structure of this polysaccharide, however, it self-assembled into a homogenous nanoparticle with a diameter of ~600 nm. The solution behavior of this AssP polysaccharide was simulated, and there was no specific binding site on one molecule for another. Association of this polysaccharide was concentration dependent. As the AssP concentration increased, the spherical particles increased their sizes and eventually merged into cylindrical micelles. The diversity of AssP hydrodynamic behavior endowed potential versatility in its applications.Conclusions: AssP was characterized as a polysaccharide with identified monosaccharide compositions and linkage between them. Although there is no tertiary structure in one AssP molecule, self-assembly of AssP molecules could form nanoparticles or micelles depending on its solution concentrations. The unique AssP solution behavior endows itself a potential biomaterial for nanoparticles preparations.

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Chemical composition of Allium schoenoprasum leaves and inhibitory effect of their extract on tumor growth in mice

Cited by 16 publications

References 5 publications

Antioxidant Properties and Structure-Antioxidant Activity Relationship of Allium Species Leaves

Antioxidant Properties and Structure-Antioxidant Activity Relationship of Allium Species Leaves

Polyphenolic Extracts of Edible Flowers Incorporated onto Atelocollagen Matrices and Their Effect on Cell Viability

Purification, Characterization, and Self-Assembly of the Polysaccharides from Allium Schoenoprasum

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