Chemical composition of Lepidium meyenii

Dini, Antonio; Migliuolo, G.; Rastrelli, Luca; Saturnino, Paola; Schettino, O

doi:10.1016/0308-8146(94)90003-5

Cited by 158 publications

(171 citation statements)

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“…The nutritional value of dried Maca hypocotyls is high (Li et al 2001). Dry Maca hypocotyls have 59% carbohydrates, 10·2% proteins, 8·5% fiber, 2·2% lipids and a number of other compounds, including most of the essential amino acids (Dini et al 1994). Arginine, a constituent of Maca, has been clinically proven to play a role in male fertility (Scibona et al 1994).…”

Section: Coefficient Of Regression Significancementioning

confidence: 99%

Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m)

Gonzales¹,

Gasco²,

Cordova³

et al. 2004

Journal of Endocrinology

132

127

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Lepidium meyenii (Maca) is a Peruvian hypocotyl that grows exclusively between 4000 and 4500 m in the central Andes. Maca is traditionally employed in the Andean region for its supposed fertility-enhancing properties.The aim of this study was to test the hypothesis that Maca can prevent high altitude-induced testicular disturbances. Adult male rats were exposed for 21 days to an altitude of 4340 m and treated with vehicle or aqueous extract of Maca (666·6 mg/day). The lengths of the stages of the seminiferous epithelium and epididymal sperm counts were obtained at 0, 7, 14 and 21 days of exposure. The stages of the seminiferous tubules were assessed by transillumination. A dose-response study was also performed at sea level to determine the effect of Maca given to male rats at doses of 0, 6·6, 66·6 and 666·6 mg/day for 7 days on body weight, seminiferous tubule stages and epididymal sperm count. The length of stage VIII and the epididymal sperm count were increased in a dosedependent manner in Maca-treated rats but treatment reduced the length of stage I. At the highest dose, sperm count increased 1·58 times, the length of stage VIII increased 2·4 times and the length of stage I was reduced 0·48 times compared with the value at dose 0. Exposure to high altitude resulted in a reduction in epididymal sperm count after 7 days and lower values were maintained up to 21 days. Altitude reduced spermiation (stage VIII) to half and the onset of spermatogenesis (stages IX-XI) to a quarter on days 7 and 14 but treatment with Maca (666·6 mg/day) prevented these changes. Data on transillumination and epididymal sperm count in the Macatreated group exposed to high altitude were similar to those obtained at sea level. Maca increased the sperm count on day 21 of exposure to high altitude to values similar (1095·25 20·41 10 6 sperm, means S.E.M.) to those obtained in the Maca-treated group at sea level (1132·30 172·95 10 6 sperm). Furthermore, in the Maca-treated group exposed for 21 days to high altitude, epididymal sperm count was higher than in the nontreated group at sea level (690·49 43·67 10 6 sperm). In conclusion, treatment of rats with Maca at high altitude prevented high altitude-induced spermatogenic disruption.

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Section: Coefficient Of Regression Significancementioning

confidence: 99%

Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m)

Gonzales¹,

Gasco²,

Cordova³

et al. 2004

Journal of Endocrinology

132

127

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“…Maca has recently been studied profusely because of the diverse pharmacological properties, such as fertility enhancer, sexual performance effects, and endurance capacity enhancer (Cicero et al 2001;BustosObregón et al 2005;Ruiz-Luna et al 2005). The maca root contains high nutritional value component (Dini et al, 1994) and several unique secondary metabolites, such as macamides, macaene, alkaloids, glucosinolates, and sterols (Ganzera et al 2002;Muhammad et al 2002;Piacente et al 2002;Cui et al 2003).…”

Section: Introductionmentioning

confidence: 99%

Effects of macamides on endurance capacity and anti-fatigue property in prolonged swimming mice

Yang

Jin

et al. 2015

Pharmaceutical Biology

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Objective: The present study investigates the effects of macamides on endurance capacity and antifatigue property in prolonged swimming mice. Materials and methods: The Balb/c mice were divided into seven groups: a control group, low-dose groups of N-benzyllinoleamide, N-benzyloleamide, and N-benzylpalmitamide, high-dose groups of these macamides. The macamides groups received the commercial products (12 and 40 mg/kg, ig), while the control group received vehicle for 21 d. On the 14th day, the mice were given the weightloaded swimming test. On the 21st day, the mice were sacrificed immediately after 90 min swimming, and some biochemical parameters were measured. Results and discussion: Compared with the control group, exhaustive swimming time was significantly prolonged in high-dose group of N-benzyloleamide (p50.05); the levels of lactic acid (LD), blood ammonia (BA), and lactate dehydrogenase (LDH) were significantly decreased (p50.05), whereas the levels of liver glycogen (LG) and non-esterified fatty acid (NEFA) were significantly increased (p50.05) in high-dose group of N-benzyloleamide. The malondialdehyde (MDA) contents in the brain, muscle, and liver were significantly decreased (p50.05), whereas superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) activities in the brain, muscle, and liver were significantly increased in high-dose group of N-benzyloleamide (p50.05). Conclusion:The results indicate that N-benzyloleamide has pharmaceutical property against exercise-induced fatigue, and this effect can be explained by the modulated energy metabolism and improved antioxidant status.

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“…Al comparar la fecundidad de los adultos de C. externa bajo las dietas L+M, L+K y M+K con la dieta estándar, indicó que con las tres dietas se obtuvieron cantidades estadísticamente similares de huevos totales (Cuadro 5). Por ende, la harina de maca y la harina de kiwicha serían un buen complemento nutricional de la levadura, por presentar un alto contenido de proteínas y de aminoácidos esenciales (Bressani et al 1987, Dini et al 1994, Escudero et al 2004, obteniéndose así una adecuada dieta, la cual permite una mayor capacidad de oviposición (Lizárraga & Cañedo 1988). Ulhaq et al (2006) indican que el azúcar es un componente muy importante en la dieta de los adultos y que produce efectos pronunciados en la producción de huevos.…”

Section: Días Promedio De Huevosunclassified

Efecto de dietas artificiales en la biología de adultos de chrysoperla externa (hagen, 1861) (neuroptera: chrysopidae)

Soto

Iannacone

2008

AZM

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Se evaluó bajo condiciones de laboratorio el efecto de ocho dietassobre la biología de adultos de Chrysoperla externa (Hagen, 1861) (Neuroptera: Chrysopidae) con el fin de determinar una dieta artificial barata y efectiva. Una dieta estándar con levadura y siete constituidas por maca (Lepidium meyenii Walpers), soya (Glycine max (Linnaeus) Merril) y kiwicha (Amaranthus caudatus Linnaeus); en las siguientes combinaciones: levadura y maca; levadura y kiwicha; levadura y soya; levadura, maca y kiwicha; levadura, maca y soya; levadura, soya y kiwicha; y levadura, maca, soya y kiwicha fueron evaluadas con respecto a la biología de adultos de C. externa. Todas las dietas contenían miel de abejas, polen y agua. Se evaluó la influencia de las dietas de los adultos en la viabilidad de los huevos, capacidad de oviposición, ritmo de oviposición, periodo de pre-oviposición, periodo de oviposición, periodo de post-oviposición de las hembras y longevidad de hembras y machos, durante dos generaciones de C. externa. Las ocho dietas evaluadas obtuvieron una elevada viabilidad de huevos en condiciones de laboratorio. Sin embargo, las dietas estandarizada a base de levadura, levadura + kiwicha, y soya + kiwicha obtuvieron una más alta viabilidad de huevos. Las dietas a base de levadura, levadura + maca, levadura + kiwicha, y a base de maca y kiwicha fueron con las que se obtuvo la mayor capacidad de oviposición. En general, no existieron diferencias significativas entre los periodos de preoviposición, oviposición y post-oviposición bajo las ocho dietas artificiales para C. externa, con tendencia a ser más altos en la segunda generación. Las dietas de levadura con maca, levadura, maca, soya y kiwicha permitieron un aumento en la longevidad de las hembras y machos para la segunda generación.

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Chemical composition of Lepidium meyenii

Cited by 158 publications

References 1 publication

Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m)

Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m)

Effects of macamides on endurance capacity and anti-fatigue property in prolonged swimming mice

Efecto de dietas artificiales en la biología de adultos de chrysoperla externa (hagen, 1861) (neuroptera: chrysopidae)

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