Chemical Constituents and Anti-Ulcer Activity of Ethylacetate Extract of the Leaves of Sanchezia nobilis Hook.F.

Abstract

Sanchezia nobilis Hook.F. is being paid attention and studied in a lot of different ways. The research of Abu Shuaib Rafshanjani and partners about the evaluation of the safety of Brine shrimp lethality bioassay method on n-hexane and ethylacetate segments, the results showed that both segments were safer than vincristine sulphate. 1 With antimicrobial, antifungal and insecticidal testing by diffusion on agar plates with 15 strains of Gram (+) and Gram (-) bacteria; 6 strains of fungus and insects Tribolium castaleum was not as good as comparison antibiotics. 2 Mohammad javad Paydar and co-worker have tried the antioxidant effect by Oxygen Radical Antioxidant Capacity (ORAC) method, the results were nearly equal to Quercetin and anti-cancer on methanolic segment from Sanchezia speciosa extract on MCF-7, SK-MEL-5, HUVEC giving the best results on CMF-7 cell lines, the anti-cancer effect on Hela cells from the roots of Sanchezia nobilis produced good results by MTT of Nusrat Shaheen and co-worker. 3,4 Research on the antioxidant effect of DPPH and anti-inflammatory by inhibition of albumine denaturation assay method by Bui Thanh Tung and partners gave positive results. 5 Some new claims showing that Sanchezia nobilis Hook.F. contains a number of substance groups such as flavonoids, glycosides, carbohydrates, alkaloids, steroids, phenolic, saponins and tannins. Some specific substances were isolated such as 5 matsutake alcohol compounds, in which the four compounds were first isolated from the Acathanceae family and one was the first isolated from nature, 3-O-arabarabinopyranosyl-(1-6)-β-glucopyranosyl-(1-6)-β-glucopyranosyl-1-octen-3-ol and 6 other compounds from the leaf and root methnol extract, in which 1 substance was first isolated from naturally, 9-O-β-xylopyranosyl-(1→6)-O-βglucopyranosyl-(1→6)-O-β-glucopyranosyltranscinnamyl alcohol, the 4 substances were first isolated from the Acanthaceae family and 3 substances were reported for the first time from Sanchezia by Ahmed and co-worker Bui Thanh Tung and partners also isolated 4 compounds in which 3 compounds were first isolated from Sanchezia speciosa. 6-8 In Vietnam, Sanchezia are found in many localities such as

Phenolic Compounds from Caesalpinia sappan

“…The NMR data of 1 are in accordance with the data reported in the literature for sappanchalcone 15 , 2 for caesalpiniaphenol G 16 , and 3 for quercetin. 17 Compound 1 was obtained as a yellow powder. The belonging to two tri-substituted benzene rings, one methoxyl group at δ H 3.85 (3H, s).…”

“…The 1 H NMR spectrum of 3 displayed five aromatic proton signals, including two meta-coupled proton signals at δ H 6.20 (1H, d, J = 2.0 Hz, H-6) and 6.41 (1H, d, J = 2.0 Hz, H-8) ascribed to the 5,7-dihydroxylated ring A from a flavonoidic skeleton, an ABX system at δ H 7.64 (1H, dd, J = 8.5, 2.0 Hz, H-6ʹ), 7.75 (1H, d, J = 2.0 Hz, H-2ʹ), and 6.90 (1H, d, J = 8.5 Hz, H-5ʹ) ascribed to a 1,3,4-trisubstituted of ring B. The 13 C NMR of 3 showed the presence of 15 aromatic carbon signals.Based on the NMR data and comparison of the data given in the literature, the structure of compound 3 was identified as quercetin 17.…”