Chemical constituents and biological activities of the genus<i>Linaria</i>(Scrophulariaceae)

Cheriet, Thamere; Mancini, Ines; Seghiri, Ramdane; Benayache, Fadila

doi:10.1080/14786419.2014.999243

Cited by 34 publications

(10 citation statements)

References 53 publications

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“…Vitexin seemed to be not typical to Linaria species as it was not mentioned to be observed as Linaria species constituent and was also not detected in our experiments. Some other polyphenols reported in the bibliography were identified by reversed-phase HPLC analysis as protocatechuic acid, gallic acid, p-hydroxybenzoic acid, vanillic acid and salicylic acid, caffeic acid, pcoumaric acid, ferulic acid, homoprotocatechuic acid, O-hydroxyphenylacetic acid, gluco-syringic acid and p-methoxybenzoic acid (Cheriet et al, 2015). We were the first to detect also rosmarinic, sinapic and chlorogenic and neochlorogenic acids in L. vulgaris ethanolic extract.…”

Section: Melissa Officinalismentioning

confidence: 70%

In Vitro Screening of Antioxidant and Antimicrobial Activities of Medicinal Plants Growing in Slovakia

Gayibova¹,

Ivanišová²,

Árvay³

et al. 2019

J microb biotech food sci

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Traditional medicine usage at the preventive medicine level is comprehensive and plant-based remedies are being prescribed for the treatment of a large scale of diseases by indigenous medical practitioners around the world. The phytochemicals being observed in the fruits and vegetables as well as herbal plants are getting investigated intensively as their important role in the avoidance of diverse human diseases is undoubtful. Antioxidant and antimicrobial activities of selected medicinal herbs were evaluated in this study. Aerial parts of plants from Hypericaceae, Lamiaceae, Fabaceae, Plantaginaceae, Rubiaceae growing wild in Slovakia (locality Zobor) were investigated to characterize their polyphenol content, flavonoid content, as well as antioxidant and antimicrobial activity. Inspection of the metabolic profile combined with HPLC data showed that the ethanol extract contained mainly eight polyphenols with apigenin, daidzein, kaempferol, rutin, quercetin, vitexin, and cynaroside as the main chemicals. Among them, neochlorogenic acid, chlorogenic acid, trans-p-caffeic acid, trans-p-coumaric acid, trans-p-sinapic acid, trans-p-ferulic acid, rosmarinic acid were identified. The antioxidant capacity of ethanol extracts was evaluated by employing DPPH radical scavenging and phosphomolybdenum assays. All samples were also tested against Gram-positive (Staphylococcus aureus, Bacillus thuringiensis, Micrococcus luteus, Staphyloccocus epidermidis) and Gram-negative (Citrobacter koseri, Escherichia coli, Pseudomonas proteolytica, Hafnia alvei, Salmonella enterica, Yersinia enterocolitica) bacterial species using the disk diffusion and minimum inhibitory concentration assays

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Section: Melissa Officinalismentioning

confidence: 70%

In Vitro Screening of Antioxidant and Antimicrobial Activities of Medicinal Plants Growing in Slovakia

Gayibova¹,

Ivanišová²,

Árvay³

et al. 2019

J microb biotech food sci

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“…The plant was also used in the treatment of haemorrhoids, scurvy, as a poultice to heal wounds and the infusion of the flowers was used as a diuretic in the Canary Islands. The flowers can be made into a non-permanent yellow dye [64][65][66][67].…”

Section: Linaria Cymbalaria (Syn: Cymbalaria Muralis)mentioning

confidence: 99%

Traditional uses of Iraqi medicinal plants (part 2)

Al-Snafi¹

2021

Int. J. Biol. Pharm. Sci. Arch.

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As a result of accumulated experience from the past generations, today, all the world’s cultures have an extensive knowledge of herbal medicine. In recent years, ethno medicinal studies has received much attention as this brings to light the numerous little known and unknown medicinal virtues especially of plant origin which needs evaluation on modern scientific lines such as phytochemical analysis, pharmacological screening and clinical trials. This review was designed to highlight the traditional uses of medicinal plants.

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“…The plants belonging to Kickxia genus are well known for the presence of several metabolites such as flavonoids [ 7 , 8 ], alkaloids [ 9 ], terpenoids [ 10 ], and iridoids [ 11 ]. Several traditional uses of Kickxia species around the world have been documented, such as laxatives, diuretics, tonics, anti-diabetic, and antiscorbutic, alongside the treatment of disorders such as hemorrhoids, wounds, and vascular treatments [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

“…The plant has yellow flowers, and flowering time extends from February to June [ 13 ]. Kickxia species, including K. aegyptiaca, were documented as significant traditional plants in the treatment of vascular diseases, haemorrhoids, and wounds, along with their uses as laxatives, anti-diabetics, anti-scorbutics, diuretics, and, tonics agents [ 12 , 14 ]. The phytochemical characterization of this plant revealed that it is rich in flavonoids, phenolic acids, glycosides, and iridoids [ 7 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition of Kickxia aegyptiaca Essential Oil and Its Potential Antioxidant and Antimicrobial Activities

Abd‐ElGawad

El‐Amier

Bonanomi

et al. 2022

Plants

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The exploration of new bioactive compounds from natural resources as alternatives to synthetic chemicals has recently attracted the attention of scientists and researchers. To our knowledge, the essential oil (EO) of Kickxia aegyptiaca has not yet been explored. Thus, the present study was designed to explore the EO chemical profile of K. aegyptiaca for the first time, as well as evaluate its antioxidant and antibacterial activities, particularly the extracts of this plant that have been reported to possess various biological activities. The EO was extracted from the aerial parts via hydrodistillation and then characterized by gas chromatography-mass spectrometry (GC-MS). The extracted EO was tested for its antioxidant activity via the reduction in the free radicals, 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). In addition, the EO was tested as an antibacterial mediator against eight Gram-negative and Gram-positive bacterial isolates. Forty-three compounds were identified in the EO of K. aegyptiaca, with a predominance of terpenoids (75.46%). Oxygenated compounds were the main class, with oxygenated sesquiterpenes attaining 40.42% of the EO total mass, while the oxygenated monoterpenes comprised 29.82%. The major compounds were cuminic aldehyde (21.99%), caryophyllene oxide (17.34%), hexahydrofarnesyl acetone (11.74%), ar-turmerone (8.51%), aromadendrene oxide (3.74%), and humulene epoxide (2.70%). According to the IC50 data, the K. aegyptiaca EO revealed considerable antioxidant activity, with IC50 values of 30.48 mg L−1 and 35.01 mg L−1 for DPPH and ABTS, respectively. In addition, the EO of K. aegyptiaca showed more substantial antibacterial activity against Gram-positive bacterial isolates compared to Gram-negative. Based on the minimum inhibitory concentration (MIC), the EO showed the highest activity against Escherichia coli and Bacillus cereus, with an MIC value of 0.031 mg mL−1. The present study showed, for the first time, that the EO of K. aegyptiaca has more oxygenated compounds with substantial antioxidant and antibacterial activities. This activity could be attributed to the effect of the main compounds, either singular or synergistic. Thus, further studies are recommended to characterize the major compounds, either alone or in combination as antioxidants or antimicrobial agents, and evaluate their biosafety.

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Chemical constituents and biological activities of the genusLinaria(Scrophulariaceae)

Cited by 34 publications

References 53 publications

In Vitro Screening of Antioxidant and Antimicrobial Activities of Medicinal Plants Growing in Slovakia

In Vitro Screening of Antioxidant and Antimicrobial Activities of Medicinal Plants Growing in Slovakia

Traditional uses of Iraqi medicinal plants (part 2)

Chemical Composition of Kickxia aegyptiaca Essential Oil and Its Potential Antioxidant and Antimicrobial Activities

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