Chemical Constituents and Biological Activities of Essential Oils of Hydnora africana Thumb Used to Treat Associated Infections and Diseases in South Africa

Wintola, Olubunmi Abosede; Afolayan, Anthony Jide

doi:10.3390/app7050443

Cited by 19 publications

(14 citation statements)

References 20 publications

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“…Chen et al [57] also reported that methyl benzoate has insecticidal properties against pest insects and mites. Save et al [58] reported that 1, 2-benzenedicarboxylic acid, butyl octyl ester, can be used in drug development for arthritis, microbial allergies, and cancer, whereas it can also be used as an antioxidant and antimicrobial agent [59]. 8-Octadecenoic acid methyl ester (E) showed antioxidant and antimicrobial activity and also effects of the serum lipid in women during lactation period [60,61].…”

Section: Gas Chromatography-mass Spectrometry Analysismentioning

confidence: 99%

Mycochemical Screening and Analysis, Antioxidant Activity, and Biochemical Composition of Fermentation Strain Snef1216 (Penicillium chrysogenum)

Sikandar

Zhang

Wang

et al. 2020

Journal of Analytical Methods in Chemistry

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Antioxidants are the radical scavengers that inhibit peroxidation and other free-radical processes, which in return safeguard different organisms from various diseases attributed to radical reactions. Synthetic antioxidants inhibit free radicals, but they also have harmful side effects. However, mycochemicals of natural fungal origin are safe and best substitutes for harmful synthetic chemical antioxidants. The prime objectives of the study include appropriate qualitative and quantitative mycochemical screening, antioxidant potential, and chemical composition of Snef1216 (Penicillium chrysogenum). The study has used aluminium chloride colourimetric method, Folin–Ciocalteu reagent assay, and DPPH (1,1-diphenyl-1-picrylhydrazyl) for analysis of total flavonoid content and phenol content and antioxidant activity, respectively. However, the presence of biologically active compounds was screened through gas chromatography-mass spectrometry (GC-MS). Quantitative analysis demonstrated the existence of flavonoids, glycosides, flavones, saponins, phenols, and catecholic tannins excluding alkaloids, terpenoids, steroids, and gallic tannins. The outcomes exposed total flavonoid content and phenolic content in P. chrysogenum were 85.31 ± 1.23 mg·QE/g and 135.77 ± 1.14 mg·GAE/g, respectively. Snef1216 (P. chrysogenum) displayed the highest free-radical scavenging activity with 63.86% inhibition of DPPH. The analysis confirms that Snef1216 (P. chrysogenum) is an alternative source of natural antioxidants. The obtained data have provided the foundation for its use in agricultural, environmental, and pharmaceutical industries.

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Section: Gas Chromatography-mass Spectrometry Analysismentioning

confidence: 99%

Mycochemical Screening and Analysis, Antioxidant Activity, and Biochemical Composition of Fermentation Strain Snef1216 (Penicillium chrysogenum)

Sikandar

Zhang

Wang

et al. 2020

Journal of Analytical Methods in Chemistry

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“…Researchers have shown that the volatile oils of different plant organs have antitumorigenic, insecticidal, antifungal, anticarcinogenic, antibacterial, anti-inflammatory, antiparasitic, antiviral and antioxidant properties. [81,90,101,102,106] Table 2 represents the collection of literature data concerning essential oil composition of Laggera spe- Aerial EtOH Eudesmane sesquiterpenes: 1β,9β-Dihydroxy-4αH-eudesma-5,11(13)-dien-12-oic acid; 1β,3α-dihydroxyeudesma-5,11(13)-dien-12-oic acid; 2β-hydroxyilicic acid; Eudesmane sesquiterpene glucosides: Eudesmane sesquiterpenes: 3β,4α-Dihydroxy-7-epi-eudesm-11(13)-ene; 3αangeloyloxy-4α,11-dihydroxyeudesm-6-en-8-one; 3α-(2',3'-dihydroxy-2'-methylbutanoyl)-4,11-dihydoxy-6,7-dehydroeudesman-8-one; 3α-(3'-chloro-2'hydroxy-2'-methylbutanoyl)cuauthemone [65] [a] NR, Not reported. cies from different countries.…”

Section: Essential Oil Constituentsmentioning

confidence: 99%

The genus Laggera (Asteraceae) – Ethnobotanical and Ethnopharmacological Information, Chemical Composition as well as Biological Activities of Its Essential Oils and Extracts: A Review

Getahun

Sharma

Gupta

2019

Chemistry & Biodiversity

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Most species of the genus Laggera are often used in traditional and folk medicines for the treatment of jaundice, inflammation, leukemia, removing phlegm, bronchitis and bacterial diseases. The essential oils obtained from Laggera plants are rich sources of oxygenated monoterpenes and sesquiterpenes. Among oxygenated monoterpenes, aromatic ether 2,5‐dimethoxy‐p‐cymene is the most abundant and dominant compound of many essential oils of the Laggera species. Till today, to the best of our knowledge, chemical compounds of the essential oils and/or extracts of only eight Laggera species were reported from different countries. Thus, this review presents the chemical compositions and biological activities of the essential oils of these plants studied in thirteen countries. In addition, it discusses the reported ethnobotanical and ethnopharmacological information as well as biological activities of the extracts and some of the isolated compounds of Laggera plants species.

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“…H. arabica is distributed from Southern Oman (Dhofar region) to Yemen on Acacia species [ 1 ]. H. africana is distributed in Namibia, Swaziland, Nigeria, Kenya, Zimbabwe, Uganda, Madagascar, Saudi Arabia, South Africa, and Ethiopia [ 8 , 12 , 25 , 43 , 47 , 48 ]. H. abyssinica is the most widely distributed species in Namibia, Northern Botswana, Zimbabwe, Zaire, Tanzania, Kenya, Ethiopia, Somalia, Sudan, and the Arabian Peninsula [ 11 , 23 , 24 , 29 , 40 , 49 , 50 , 51 ].…”

Section: Host Specificity Concerning Species Distributionmentioning

confidence: 99%

“…Moreover, the flowers of H. abyssinica are used as wild food and in traditional medicine in South Yemen [ 24 ]. Therapeutic properties, for instance, antibacterial, antifungal, antioxidant, and antiproliferative activities, have been reported in H. abyssinica and H. africana [ 25 , 26 , 27 , 28 ]. Regardless of the ethnobotanical value and medicinal significance of the Hydnora species, little effort has been made to integrate all of the relevant available data.…”

Section: Introductionmentioning

confidence: 99%

Understanding the Ethnobotany, Chemistry, Pharmacology, and Distribution of Genus Hydnora (Aristolochiaceae)

Mkala

Mutungi

Mutinda

et al. 2021

Plants

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The genus Hydnora (Hydnoraceae) is one of the basal angiosperms in the order Piperales, found in the semi-arid regions of Africa, and the Southern Arabian Peninsula. Plants in this genus play essential roles in communities around the world as revealed by various studies. Currently, there are eight species of the genus Hydnora; seven in Africa and one in the Arabian Peninsula. Notably, Hydnora abyssinica A.Br. and Hydnora africana Thunb. are widely distributed compared to other species. They are widely used for their medicinal and nutritional values. The information on ethnobotany, chemistry, pharmacology, and distribution of genus Hydnora was gathered using phytochemical and ethnobotanical books, electronic sources, and published articles. Preliminary phytochemical screening shows that flavonoids, phenolics, proanthocyanidins, and tannins are the main compounds in H. abyssinica and H. africana. Furthermore, 11 compounds have been isolated from H. abyssinica. The biological activities of H. abyssinica and H. africana have been reported. They include antibacterial, antiproliferative, antioxidant, antidiarrhea, and antifungal potentials. Despite the Hydnora species being practiced in ancient folkloric medicine, their traditional uses and pharmacological value are poorly documented. Based on the available information on ethnobotany, phytochemistry, pharmacology, and distribution, we aim to provide research gaps and challenges for a better understanding of this genus. This may be resourceful in the development of effective phytomedicines, and aid in conservation. The available studies on this genus on some aspects such as phytochemistry, pharmacological activities, and distribution are under-reported hence the need for further research.

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Chemical Constituents and Biological Activities of Essential Oils of Hydnora africana Thumb Used to Treat Associated Infections and Diseases in South Africa

Abstract: Hydnora africana (HA) Thumb is a member of the genus Hydnora.

Cited by 19 publications

References 20 publications

Mycochemical Screening and Analysis, Antioxidant Activity, and Biochemical Composition of Fermentation Strain Snef1216 (Penicillium chrysogenum)

Mycochemical Screening and Analysis, Antioxidant Activity, and Biochemical Composition of Fermentation Strain Snef1216 (Penicillium chrysogenum)

The genus Laggera (Asteraceae) – Ethnobotanical and Ethnopharmacological Information, Chemical Composition as well as Biological Activities of Its Essential Oils and Extracts: A Review

Understanding the Ethnobotany, Chemistry, Pharmacology, and Distribution of Genus Hydnora (Aristolochiaceae)

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