Chemical constituents from the fruiting branches of Artocarpus nanchuanensis endemic to China

Ren, Gang; Hu, Zhi-Cheng; Xiang, Heng-Yun; Peng, Jia-Bing; Liu, Ronghua; Huang, Huilian; Shao, Feng

doi:10.1016/j.bse.2013.08.019

Cited by 4 publications

(2 citation statements)

References 20 publications

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“…Artocarpus nanchuanensis (NCBI:txid1745975), which is mainly distributed in Chongqing Nanchuan, is part of a new generation of southern urban greening tree species; this species has high quality and excellent fast-growing characteristics, which allow it to live in acidic soil and environments with heavy atmospheric pollution due to it strong ability to resist pollution and disease [ 1 , 2 ]. The fruit of A. nanchuanensis contains a variety of polysaccharides, amino acids, trace elements, and vitamins, which have a good control effect on constipation and other intestinal diseases [ 2 ]. The fruit and bark have been used in the treatment of skin diseases in Chongqing Nanchuan for a long time.…”

Section: Introductionmentioning

confidence: 99%

A chromosome-level genome assembly of Artocarpus nanchuanensis (Moraceae), an extremely endangered fruit tree

Bao

Deng

et al. 2022

GigaScience

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Artocarpus nanchuanensis (Moraceae), which is naturally distributed in China, is a representative and extremely endangered tree species. In this study, we obtained a high-quality chromosome-scale genome assembly and annotation information for A. nanchuanensis using integrated approaches, including Illumina, Nanopore sequencing platform, and Hi-C. A total of 128.71 Gb of raw Nanopore reads were generated from 20-kb libraries, and 123.38 Gb of clean reads were obtained after filtration with 160.34× coverage depth and a 17.48-kb average read length. The final assembled A. nanchuanensis genome was 769.44 Mb with a 2.09 Mb contig N50, and 99.62% (766.50 Mb) of the assembled data was assigned to 28 pseudochromosomes. In total, 39,596 genes (95.10%, 39,596/41,636) were successfully annotated, and 129 metabolic pathways were detected. Plants disease resistance/insect resistance genes, plant–pathogen interaction metabolic pathways, and abundant biosynthesis pathways of vitamins, flavonoid, and gingerol were detected. Unigene reveals the basis of species-specific functions, and gene family in contraction and expansion generally implies strong functional differences in the evolution. Compared with other related species, a total of 512 unigenes, 309 gene families in contraction, and 559 gene families in expansion were detected in A. nanchuanensis. This A. nanchuanensis genome information provides an important resource to expand our understanding of the unique biological processes, nutritional and medicinal benefits, and evolutionary relationship of this species. The study of gene function and metabolic pathway in A. nanchuanensis may reveal the theoretical basis of a special trait in A. nanchuanensis and promote the study and utilization of its rare medicinal value.

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Section: Introductionmentioning

confidence: 99%

A chromosome-level genome assembly of Artocarpus nanchuanensis (Moraceae), an extremely endangered fruit tree

Bao

Deng

et al. 2022

GigaScience

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“…Its growth environment is the most extremely unique for Artocarpus species. The previous studies on the fruiting branches of A. nanchuanensis S.S. Chang led to spirostanol derivatives and tetrahydrofuran-type lignans [13]. In a program searching for new active compounds, we investigated this plant and isolated four novel stilbene derivatives, hypargystilbene B (1), hypargystilbene C (2), hypargystilbene D (3), and hypargystilbene E (4) (Figure 1), together with hypargystilbene A (5) [14], 5,7,2 0 ,4 0 -tetrahydroxyflavone (6) [15], 4-prenylmoracin (7) [16], 4-geranyl-3,5,2 0 ,4 0 -tetrahydroxy-transstilbene (8) [17], oxyresveratrol (9) [18], 3 0 ,5 0 ,2,4-tetrahydroxy-4 0 -(3-methylbutenyl)-stilbene (10) [19], and polystachyol (11) [20].…”

Section: Introductionmentioning

confidence: 99%

Novel stilbenes fromArtocarpus nanchuanensis

Zhang

2015

Journal of Asian Natural Products Research

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Four new stilbene derivatives, hypargystilbenes B-E (1-4), together with seven known compounds (5-11), were isolated from the stems of Artocarpus nanchuanensis S.S. Chang. Their structures were elucidated on the basis of spectral data. Hypargystilbene B, hypargystilbene D, and hypargystilbene E exhibited protein tyrosine phosphatase 1B inhibitory effects with corresponding IC50 values of 3.23, 37.31, and 2.53 nM.

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