Chemical Constituents from the Leaves of <i>Litsea Acutivena</i>

Tsai, Ian‐Lih; Cheng, Ming‐Jen; Hung, Hsiu-Wen; Cheng, Hsin-I; Chen, Ih-Sheng

doi:10.1002/jccs.200700071

Cited by 13 publications

(5 citation statements)

References 16 publications

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“…Investigation of the leaves of L. acutivena Hayata [ Actinodaphne acutivena (Hay.) Nakai] has led to the isolation of eight new compounds, the norneolignan dehydroxymethylailanthoidol ( 163 ); the butanolides, litseakolides D–G ( 164 – 167 ), isolincomolide D ( 168 ) [ 102 ], and acutilactone ( 169 ); and the lactone, 4-nonacosyl-dihydrofuran-2-one ( 170 ) [ 103 ].…”

Section: Phytochemical Studies Of Formosan Lauraceous Plantsmentioning

confidence: 99%

Chemical constituents and bioactivity of Formosan lauraceous plants

Chang

Chen

2016

Journal of Food and Drug Analysis

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Taiwan is rich in lauraceous plants. A review of 197 references based on the chemical analysis and bioactivity of indigenous lauraceous plants carried out by native scientists from 1963 to 2014 has been compiled. About 303 new compounds and thousands of known compounds comprising alkaloids and non-alkaloids with diverse structures have been isolated or identified from indigenous plants belonging to the 11 lauraceous genera. The volatile components, however, have been excluded from this review. This review provides an overview of the past efforts of Taiwan scientists working on secondary metabolites and their bioactivity in native lauraceous plants. The potential of lauraceous plants worthy of further study is also noted. The contents will be helpful for the chemotaxonomy of Lauraceae and be of value for the development of native Formosan lauraceous plants.

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Section: Phytochemical Studies Of Formosan Lauraceous Plantsmentioning

confidence: 99%

Chemical constituents and bioactivity of Formosan lauraceous plants

Chang

Chen

2016

Journal of Food and Drug Analysis

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“…Assignment of signals was facilitated by COSY, HSQC and HMBC experiments. The known compounds obtained in this study, phytol acetate (1) (Itoh et al, 2003), triacontanol (2), (Tsai et al, 2007), phytol (3) (Itoh et al, 2003), and alpha kosin (5) (Woldemariam et al, 1992) were identified by comparison of their physical and spectroscopic data with literature reports.…”

Section: Identification Of Isolated Compoundsmentioning

confidence: 99%

The potential of Leucosidea sericea against Propionibacterium acnes

Sharma

Kishore

Hussein

et al. 2014

Phytochemistry Letters

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Highlights:· Significant anti-bacterial and antioxidant activity displayed by crude extract of Leucosidea sericea and isolated compound. · Electron microscopy studies proved the lethal effects of plant extract and compound 5 on the cells of P. acnes. 2 Graphical abstractAntibacterial bioassay of ethanol extract of Leucosidea sericea and isolated compounds against Propionibacterium acnes. · AbstractThe present study reports on the potential of Leucosidea sericea addressing acne vulgaris.Four known compounds namely, phytol acetate, triacontanol, phytol and alpha kosin and one new compound namely, (E)-3,7,11,15-tetramethylheptadec-2-ene-1,1 7-diol have been isolated for the first time from this plant. The ethanol extract of leaves and one of the isolated compounds, alpha kosin exhibited significant minimum inhibitory concentration (with MIC values 15.7 and 1.9 µg/mL, respectively) against acne inducing bacteria, Propionibacterium acnes. Moreover, the transmission electron micrographs showed the efflux of intracellular content of the cells of P. acnes caused by plant extract and alpha kosin. The ethanol extract of L. sericea exhibited significant anti-inflammatory activity by suppressing interleukin 8 (IL 8) and tumour necrosis factor (TNF α) in coculture of human U937 cells and heat killed P.acnes at concentrations of 25.0, 12.5 and 6.2 µg/mL.

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“…In previous studies, the stems were found to contain a novel cyclopentenone, 5-dodecanyl-4-hydroxy-4-methyl-2cyclopentenone [2], glycerols, flavanols, lactones and acyclic monoterpene diols [1,3]. As part of our continuing investigation of Formosan Lauraceous plants, a new lignan, (+)-diasesamin (1), together with eight known compounds, (+)-sesamin (2) [4], (+)-episesamin (3) [5], stearic acid (4) [6], palmitic acid (5) [7], a mixture of β-sitosterol (6) and stigmasterol (7) [8], and a mixture of β-sitosterol-Dglucoside (8) and stigmasterol-D-glucoside (9) [9] were isolated from the stem extracts of this plant. Compounds 3-9 were reported for the first time from this species.…”

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confidence: 99%

Lignans from the Stem of Cinnamomum camphora

Hsieh

Chen

et al. 2006

Natural Product Communications

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Diasesamin (1), (+)-sesamin (2), (+)-episesamin, stearic acid, palmitic acid, a mixture of β-sitosterol and stigmasterol, and a mixture of β-sitosterol-D-glucoside and stigmasterol-D-glucoside were isolated from the stems of Cinnamomum camphora (L.) Presl.. Among these compounds, 1 is obtained for the first time from a natural source. The cytotoxicity of 2 on Hep G2 and HeLa cell cancer lines was also investigated. The flow cytometric assay results indicated that 2 elicited a decrease in the percentage of the S phase of the cell cycle in Hep G2 cells after incubation for 24 h. These results reflect that 2 inhibited the DNA synthetic event in Hep G2 cells.

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Chemical Constituents from the Leaves of Litsea Acutivena

Cited by 13 publications

References 16 publications

Chemical constituents and bioactivity of Formosan lauraceous plants

Chemical constituents and bioactivity of Formosan lauraceous plants

The potential of Leucosidea sericea against Propionibacterium acnes

Lignans from the Stem of Cinnamomum camphora

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