Chemical constituents of Cyrtomium fortumei (J.) Smith

Abstract

Five known compounds, 6'-methylglucuronide-5-hydroxy-chromone (1), ethyl α-d-glactopyranoside (2), neoechinulin A (3), 9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid (4) and phellopterin (5), were isolated from water extract of Cyrtomium fortumei (J.) Smith. Compounds 1-5 were isolated from this genus for the first time, and all the compounds were evaluated in vitro against a panel of human cancer cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Among them, compounds 3 and 4 exhibited significant cytotoxic activities, with IC50 values of 15.2 and 18.3 μg/mL on MGC-803 cells, respectively.

Anti-Inflammatory Activity of Compounds Derived from Vitex rotundifolia

“…In addition, 19 other compounds were isolated and their structures were identified as 4-hydroxybenzoic acid ( 2 ) [ 14 , 15 ], 4′-hydroxyacetophenone ( 3 ) [ 16 ], 4-hydroxybenzoic methyl ester ( 4 ) [ 15 ], protocatechuic acid ( 5 ) [ 17 ], vanillic acid ( 6 ) [ 18 ], trans-4-hydroxycinnamic acid ( 7 ) [ 19 ], 3-(β-D-glucopyranosyloxymethyl)-2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxy-(2R,3S)-dihydrobenzofuran ( 8 ) [ 20 ], chrysosplenol D ( 9 ) [ 21 ], artemetin ( 10 ) and casticin ( 11 ) [ 22 ], luteolin ( 12 ) and luteolin-7-glucopyranoside ( 13 ) [ 23 ], luteolin-5-glucopyranoside ( 14 ) [ 24 ], orientin ( 15 ) [ 25 ], vitedoin A ( 16 ) [ 6 ], ethyl α-D-glactopyranoside ( 17 ) [ 26 ], ethyl β-D-glucopyranoside ( 18 ) [ 27 ], betulinic acid ( 19 ) [ 28 ], and ursolic acid ( 20 ) [ 29 ] by comparing their spectroscopic data to those reported in the literature. Among them, compounds 6 − 8 , 10 , 13 , and 17 − 20 were isolated from V .…”