Chemical Examination of the Leaves of Cαreyα αrboreα

Basak, Amitabh; Banerjee,; Bose, Lekshmi; Basu, Kaushik

doi:10.5281/zenodo.6396123

1976

DOI: 10.5281/zenodo.6396123

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Chemical Examination of the Leaves of Cαreyα αrboreα

Amitabh Basak¹,

Banerjee Banerjee²,

Lekshmi Bose³

et al.

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Cited by 2 publications

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Effect of Careya arborea Roxb. on CCl4 induced liver damage in rats

Nanotkar¹,

Jangde²,

Jagtap³

et al. 2016

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The aqueous extract of bark of Careya arborea Roxb., locally known as Kumbhi, was screened for hepatoprotective activity against CCl 4 -induced hepatotoxicity in rats with a view to explore its application for treatment of liver disorders in animals and human beings. The hepatotoxicity induced by administration of carbon tetrachloride (CCl 4 ) as 30 % solution prepared in liquid paraffin and administered subcutaneously 1ml/kg b.wt. at every 72 h interval till the completion of experiment. The hepatotoxicity was found to be tolerated by simultaneous oral administration of aqueous extract of C. arborea (AECA) stem bark (100, 200 mg/kg b. wt.) for two weeks, with evidence of decreased level of AST, ALT, ALP and bilirubin. In addition, severe histomorphological disruption and fatty changes produced by CCl 4 in respect of cytoarchitecture were minimized and maintained by the treatment of extract. The results were compared with standard drug silymarine. The results of this study showed that AECA could afford hepatoprotective activity against CCl 4 induced liver damage in rats due to nutraceutical nature of plant.

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Effect of Careya arborea Roxb. on CCl4 induced liver damage in rats

Nanotkar¹,

Jangde²,

Jagtap³

et al. 2016

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CNS activity of the methanol extracts of Careya arborea in experimental animal model

Sambathkumar¹,

Sundram²,

Pandian³

et al. 2008

Bangladesh J Pharmacol

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Chemical Examination of the Leaves of Cαreyα αrboreα

Cited by 2 publications

References 0 publications

Effect of Careya arborea Roxb. on CCl4 induced liver damage in rats

Effect of Careya arborea Roxb. on CCl4 induced liver damage in rats

CNS activity of the methanol extracts of Careya arborea in experimental animal model

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