Chemical investigation of the essential oil of Laggera crispata (Vahl) Hepper & Wood from India

Abstract

Hydrodistilled essential oil of the aerial parts of Laggera crispata (Vahl) Hepper & Wood, collected from the Kumaon region of the western Himalayas was analysed by gas chromatography and gas chromatography-mass spectrometry. Eighty constituents, accounting for 83.9 % of the total oil composition, were identified. The oil was mainly dominated by sesquiterpenoids (45.3 %) and benzenoid compounds (33.9 %). Among them, 2,5-dimethoxy-p--cymene (32.2 %), 10-epi-γ-eudesmol (14.7 %), β-caryophyllene (6.9 %) and caryophyllene oxide (5.4 %) were major components of the oil.

Chemical composition, and antibacterial and antioxidant activities of essential oils from Laggeratomentosa Sch. Bip. ex Oliv. et Hiern (Asteraceae)

“…Surprisingly, the constituents of both oils (especially their dominant compounds) differed from that of the EO isolated from the leaf and inflorescence of the same plant [10]. The dominant components of this oil were chrysanthenone [24], the leaves (27.7%) of L. aurita of Burkina-Faso [25], the leaves (33.4%) of L. gracilis, the roots (67.8%) and stems (36.5%) of L. oloptera of Cameroon [21], the aerial parts (43.2%) [26] and (32.2%) [27], the leaves (22.28%), flowers at bud stage (48.99%), flowers at full bloom/shattering stage (64.01%), stems (62.81%) and roots (75.55%) [28] of L. crispata of India. However, the essential oils of the studied Laggera species showed different chemical classes of compounds [2].…”

Essential Oil from Arnica Montana L. Achenes: Chemical Characteristics and Anticancer Activity

“…Essential oils with this compound as a major component have antibacterial, antifungal, and insecticidal properties [63,64,65]. 2,5-dimetoxy-p-cymene is a dominant component of EO Eupatorium triplinerve [62], Bubonium imbricatum [63], Ayapana triplinervis [66], Pulicaria mauritanica [67], Limbarda crithmoides [68], and Laggera crispata [69]. Therefore, it probably plays an essential role in the anticancer activity of EO in relation to the MOGGCCM and T98G cell lines.…”

The genus Laggera (Asteraceae) – Ethnobotanical and Ethnopharmacological Information, Chemical Composition as well as Biological Activities of Its Essential Oils and Extracts: A Review

“…[16][17][18] In India, the genus is represented by three species commonly found in tropical regions in both flatland and altitudes up to about 1500 m. These are L. alata, L. aurita and L. crispata. [19] Only two species such as L. aurita and L. alata are found growing in Pakistan. [20] L. pterodonta and L. alata are the only species in China.…”

“…[28] L. alata characterized with broad, entire, continuous wings and aromatic plant in nature is widespread in the highlands and east coastal region of Madagascar. [19,29] It is a strongly aromatic stout herb with a persistent thymol-like and sweet odor. [30] L. tomentosa is a perennial fragrant bushy herb or sub shrub, growing 0.5 -1.2 m high, aromatic plant with narrowly winged (wings continuous, 1 -1.5 mm wide), densely tomentose, ashy green or grey leaves.…”

“…[110] Essential oil of L. crispata of India was chiefly dominated by sesquiterpenoid (45.3 %) and benzenoid (33.9 %) compounds. [19] The oil of L. alata of Kenya was found to contain a high concentration of sesquiterpenes (50.3 %). [72] While that of L. aurita of Burkina-Faso affords mainly sesquiterpene hydrocarbons (33 %).…”