Chemical shift MR imaging in the lumbar vertebra: the effect of field strength, scanner vendors and flip angles in repeatability of signal intensity index measurement

Xiao, Zhang; Li, Jian; Li, Chengqi; Zhang, Yuyang; She, Dejun; Cao, Dairong

doi:10.1186/s12880-016-0167-3

Cited by 6 publications

(3 citation statements)

References 29 publications

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“…Chemical shift imaging aims to separately detect protons that process with similar yet slightly different frequencies, namely, those of water and fat (101). A study evaluating the reproducibility of signal intensity index (SII) measurements in healthy volunteers with MRI systems from different vendors and with different field strengths found intra-and inter-observer correlation coefficients ranging from 0.82 to 0.98 (102). In osteoporosis, the few studies performed until now have primarily assessed the bone marrow (103)(104)(105).…”

Section: Mrimentioning

confidence: 99%

Quantitative imaging methods in osteoporosis

Oei

Koromani

Rivadeneira

et al. 2016

Quant. Imaging Med. Surg.

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Section: Mrimentioning

confidence: 99%

Quantitative imaging methods in osteoporosis

Oei

Koromani

Rivadeneira

et al. 2016

Quant. Imaging Med. Surg.

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“…Fifth, MRI machines from two different vendors were used. A study stated that vendors and the magnetic field strength of MR units did not lead to a significant difference in signal intensity index [ 20 ]. Thus, we assume that the difference in the vendor did not have a notable impact.…”

Section: Discussionmentioning

confidence: 99%

FDG-PET vs. chemical shift MR imaging in differentiating intertrabecular metastasis from hematopoietic bone marrow hyperplasia

et al. 2021

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Purpose To evaluate the utility of SUVmax on FDG-PET and chemical shift imaging (CSI) on MRI in the differentiation of intertrabecular metastasis (ITM) from hematopoietic bone marrow hyperplasia (HBMH). Patients and methods We retrospectively evaluated 54 indeterminate focal bone marrow lesions in 44 patients detected on FDG-PET. The lesions were assigned to the metastasis group (M group, 29 lesions of 24 patients) and the non-metastasis group (non-M group, 25 lesions of 20 patients) based on the follow-up or the histopathological studies. The lesions were assessed with the maximum standardized uptake value (SUVmax) on FDG-PET CT images and signal change ratio (SCR) on CSI. Results The median SUVmax were 5.62 and 2.91; the median SCR were − 0.08 and − 34.8 in M and non-M groups respectively, with significant difference (p < 0.001). With ROC curve analysis, the optimal cutoff value of SUVmax was 4.48 with a sensitivity of 72.4%, a specificity of 100%, and AUC of 0.905. The cutoff value of SCR was − 6.15 with a sensitivity of 82.8%, a specificity of 80%, and AUC of 0.818. Conclusion FDG-PET and CSI on MRI are useful in distinguishing ITM from HBMH. Though their sensitivities are similar, the specificity of FDG-PET was higher than that of MRI.

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“…Chemical shift MRI is commonly used for liver and adrenal glands imaging for detecting lipid content and characterizing lesions (8)(9)(10)(11). Also, chemical shift MRI is the best sequence for differentiating malignant and benign bone marrow lesions (3).…”

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confidence: 99%

Efficacy of chemical shift MRI for differentiating diffuse red bone marrow reconversion and hematological malignancies

Akman¹,

Korkmaz²,

Sarı³

2019

Turk J Med Sci

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Introduction Normal bone marrow contains water, fat, and cellular elements. The red bone marrow (RBM) contains 40% of water (free and bound), 20% of protein, and 40% (25%-50%) of fat. In contrast, the yellow bone marrow (YBM) contains 15% of water, 5% of protein, and 80% of fat (1-4). In newborns, the bone marrow consists mainly of active RBM. After the infantile period, the RBM begins to transform into YBM. When the active bone marrow is not able to meet the increased hematopoiesis required by the body, YBM converts to RBM, and this process is called reconversion (3-7). The causes of reconversion can be classified under medical and nonmedical conditions. Medical conditions include obesity, respiratory disorders, diabetes, anemias, patients receiving granulocyte colony stimulating factor therapy, chemotherapy, and radiotherapy. Nonmedical conditions include heavy smoking and practicing sports requiring high oxygen such as marathon running or freediving (2,5-7). Magnetic resonance imaging (MRI) is an ideal noninvasive imaging modality for evaluating bone marrow Background/aim: The main purpose of our study was to determine the efficacy of chemical shift imaging (CSI) for differentiating diffuse red bone marrow reconversion (RBMR) and hematological malignancies. We also aimed to calculate the cutoff value for these entities with similar imaging features in routine magnetic resonance (MR) sequences. Materials and methods: A total of 54 patients were included: 17 patients (31.4%) with hematological malignancies (group 1), 16 patients (29.6%) with RBMR (group 2), and 21 patients (38.0%) with no clinical and hematological malignancies (control group). Patients with no pathological data or completed two-year follow-up and children were excluded from the study. An experienced radiologist on MRI evaluated the images blindly for final diagnosis. Pathologic results were determined as gold standard. Regions of interests (ROI) were placed on the vertebrae in CSI and signal intensity ratios (SIR) were calculated. The cutoff value was calculated using receiver operating characteristic (ROC) analysis. Results: SIR values were 0.97 ± 0.16, 0.69 ± 0.31 and 0.28 ± 0.35 (P < 0.001) for GI, G2, and G3, respectively. The cutoff value was 0.82 (P < 0.001). The sensitivity rate was 83.3% (AUC: 58%-96%), specificity was 87% (AUC: 58-98). Conclusion: CSI may be a valuable diagnostic tool for differentiating diffuse RBMR and hematological malignancies.

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Chemical shift MR imaging in the lumbar vertebra: the effect of field strength, scanner vendors and flip angles in repeatability of signal intensity index measurement

Cited by 6 publications

References 29 publications

Quantitative imaging methods in osteoporosis

Quantitative imaging methods in osteoporosis

FDG-PET vs. chemical shift MR imaging in differentiating intertrabecular metastasis from hematopoietic bone marrow hyperplasia

Efficacy of chemical shift MRI for differentiating diffuse red bone marrow reconversion and hematological malignancies

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