ChemInform Abstract: ALKYLATIONS OF ALKYNOLS WITH ORGANOALUMINUM REAGENTS PROMOTED BY BIS(η5‐CYCLOPENTADIENYL)TITANIUM DICHLORIDE

Abstract

Aus dem 3‐Butin‐1‐ol (I) erhält man mit Diethylaluminiumchlorid (II) eine Zwischenstufe (III), die bei der Behandlung mit Dicyclopentadienyltitandichlorid in hoher Ausbeute zu einem Gemisch der beiden Ethylierungsprodukte (IV) und (V) führt.

Diastereoselection in reactions of pinanediol dichloromethaneboronate

“…For an estimate of the 4a/5a isomer ratio, the mixture was treated with phenyllithium and the resulting mixture of (-b)-pinanediol 1-phenylpentane-l-boronates (6a and 7a) was oxidized to (R)-and (S)-l-phenyl-l-pentanol (8r and 8s), for which the absolute configuration and rotation have been established. 6 The R isomer 8r was predominant, but (6) Levene, P. A.; Marker, R. E. J. Biol. Chem.…”