ChemInform Abstract: Concise and Efficient Synthesis of Highly Potent and Selective Dipeptidyl Peptidase II Inhibitors.

Abstract

Peptides U 0400 Concise and Efficient Synthesis of Highly Potent and Selective Dipeptidyl Peptidase II Inhibitors. -A more practical, shorter, high yielding route for the synthesis of the highly potent and selective DPP II inhibitors (IX) and (XII) starts from L-glutamine. -(RASHEED*, M. A.; NAMALA, R.; MANNE, N.; VANJIVAKA, S.; DHAMJEWAR, R.; BALASUBRAMANIAN, G.; Synth. Commun. 38 (2008) 2, 162-169; GVK Biosci., IDA, Hyderabad 500 076, India; Eng.) -H. Toeppel 26-192