ChemInform Abstract: Efficient Synthesis of 2‐Substituted Thieno[2,3‐d]pyrimidin‐4(3H)‐ones via an Iminophosphorane.

Abstract

Fused pyrimidine derivatives R 0515 Efficient Synthesis of 2-Substituted Thieno[2,3-d]pyrimidin-4(3H)-ones via anIminophosphorane. -The reaction sequence proceeds via a carbodiimide formed from (V) and (VI) which is attacked by amines or alcohols to form the final products in a base-catalyzed cyclization.