ChemInform Abstract: EINFLUSS DES LOESUNGSMITTELS AUF DEN MECHANISMUS DER WURTZ‐FITTIG‐RK.

Promotion of organic reactions by ultrasound: Coupling of alkyl and aryl halides in the presence of lithium metal and ultrasound

“…Adjustments to the depth of immersion were made so that a maximum amount of agitation in the liquid was noted, and the flask was clamped firmly3 in place, A heavy precipitate of lithium bromide is formed as the reaction proceeds, Bromobenzene reacts similarly, although less vigorously, to afford biphenyl. THF is a better solvent than ether in these reactions (6), although it is often more convenient to use the latter. The cross-coupling of alkyl and aryl halides (Wurtz-Fittig reaction) may be carried out similarly (7).…”