ChemInform Abstract: Facile Heteropolyacid‐Promoted Synthesis of Indeno[1,2‐b]quinoline‐9,11(6H,10H)‐dione Derivatives.

Abstract

The title compounds, e.g. (V), are prepared by four‐ or three‐component coupling reactions.

Synthesis of indeno-[1,2-b]-quinoline-9,11(6H,10H)-dione and 7,7-dimethyl-10-aryl-7,8-dihydro-5H-indeno[1,2-b]quinoline-9,11(6H,10H)-dione derivatives in presence of heterogeneous Cu/zeolite-Y as a catalyst

“…Aer that, the Zn and Co supported catalyst was tested for its activity (Table 3 entries 19-24). Then solvents like MeOH, acetonitrile, toluene, DCM, DMF, DMSO and solventfree conditions were used for the reaction (Table 3 entries [25][26][27][28][29][30][31][32][33][34][35]. Aer checking the catalytic activity of various catalysts, the Cu/zeolite-Y catalyst was found to be efficient for this reaction.…”

“…Quinoline derivatives undergo hierarchical self-assembly into a variety of nanostructures and mesostructures with enhanced electronic and photonic functions as well as medicinal applications. 26 Indenoquinoline derivatives showed a wide range of biological activities such as 5-HT-receptor binding activity, 27 anti-inammatory activity and they also act as anti-tumor agents, 28 inhibitors for steroid reductase, 29 acetylcholinesterase inhibitors, 30 show antimycobacterial 31 and antiproliferative activities 32 and act as antimalarials. 33 Also, these compounds serve as the building blocks of many natural-chromophore DNA intercalators such as TAS 103, 34 DACA, 35,36 and NSC 314622, 37 which are currently being used as anticancer drugs.…”

“…Quinoline derivatives undergo hierarchical self-assembly into a variety of nanostructures and mesostructures with enhanced electronic and photonic functions as well as medicinal applications. 26 …”