ChemInform Abstract: Synthesis of Cytosine Derivatives and Study of Their Alkylation under Mild Conditions.

The Convenient Synthesis of 11‐Methyl‐3,8‐disubstituted‐12‐aryl‐3,4,7,8,9,12‐hexahydro‐1H‐chromeno[2,3‐b]quinoline‐1,10(2H)‐dione Derivatives

“…In this study, the 2‐arylidene‐3‐oxobutanenitrile derivatives 2 used for the current studies were easily prepared by the Knoevenagel condensation between aldehydes and 3‐oxobutanenitrile 1 , which was obtained by acid hydrolysis of β‐aminocrotononitrile . 3‐Acetyl‐2‐amino‐4 H ‐chromen‐5(6 H )‐one derivatives 3 were synthesized by reaction of 2‐arylidene‐3‐oxobutanenitrile 2 and 5,5‐dimethyl‐1,3‐cyclohexanedione in ethylene glycol.…”