ChemInform Abstract: The Synthesis of 5‐Substituted 1H‐Tetrazoles in Molten Tetrabutylammonium Bromide.

Abstract

The Synthesis of 5-Substituted 1H-Tetrazoles in Molten TetrabutylammoniumBromide. -Use of molten Bu 4NBr allows to carry out the reaction without any additional catalyst or organic solvent. The reaction protocol is not applicable to alkyl nitriles such as pentanenitrile and phenylacetonitrile. Aromatic nitriles substituted at the ortho-position require longer reaction times. -(XIE, A.; CAO, M.; FENG, L.; DONG*, W.; J. Chem. Res. 37 (2013) 11, 665-667,