ChemInform Abstract: Two New Cembranes from a Formosan Soft Coral Sinularia facile

Chen, Bo‐Wei; Su, Jui‐Hsin; Dai, Chang‐Feng; Sung, Ping‐Jyun; Wu, Yang‐Chang; Lin, Ying‐Ting; Sheu, Jyh‐Horng

doi:10.1002/chin.201216192

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2012

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“…Cembrane- and norcembrane-type natural products are major constituents of the extracts of Sinularia spp. octocorals distributed in the waters off Taiwan [ 8 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. Our continuing studies on the chemical constituents of a wild-type soft coral Sinularia sp.…”

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confidence: 99%

Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.

Yen

et al. 2012

Molecules

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Two norcembranoidal diterpenes, 5-episinuleptolide acetate (1) and scabrolide D (2), were isolated from a Formosan octocoral identified as Sinularia sp. The structures of norcembranoids 1 and 2 were established by spectroscopic methods and by comparison of the spectral data with those of known analogues and 1 was proven to be a new natural product. Norcembranoid 1 was found to exhibit cytotoxicity toward a panel of tumor cells.

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