Chemistry and application of 4‐oxo‐4H‐1‐benzopyran‐3‐carboxaldehyde

Abstract

The Chemistry and application of the title aldehyde and some simple derivatives thereof are reviewed.

Chemistry and application of 4-oxo-4H-1-benzopyran-3-carboxaldehyde

“…The present article, complementary to an earlier one 6 is a comprehensive survey of a huge number of publications that have appeared mainly since 2007 to February 2014 and it provides a quick view of the research work already done in the title topic.…”

Palladium-catalyzed synthesis of novel tetra- and penta-cyclic biologically active benzopyran- and pyridopyran-containing heterocyclic systems

“…Rms deviation of fitted atoms = 0.0066. 3-Chloromethylbenzo [4,5] (11) were obtained by the procedure described in article. 24 All prepared compounds are new and were characterized by melting point, LC-MS, HRMS, 1 H NMR and 13 C NMR spectra.…”

“…24 All prepared compounds are new and were characterized by melting point, LC-MS, HRMS, 1 H NMR and 13 C NMR spectra. General procedure for synthesis of polycyclic compounds 4a,b, 7, 10 and 13 Mixture of 2-iodophenoxymethylhetarenes 3a, 6, 9, 12 or 3-(2-bromo-pyridin-3-yloxymethyl)-benzo [4,5]imidazo[2,1-b]thiazole 3b (0.49 mmol), Pd(OAc)2 (0.011 g, 0.049 mmol), Xantphos (0.057 g, 0.098 mmol), anhydrous Cs2CO3 (0.32 g, 0.98 mmol) and Ag2CO3 (0.068 g, 0.25mmol) in dry toluene (10 mL) was heated at 120 o C for 24 h in glass reactor under argon. Reaction mixture was filtered and solvent was removed under reduced pressure.…”

“…[1][2][3] The synthesis and reactions of pyrans and benzopyrans have been well reviewed. [4][5][6][7][8][9] Recently the uses and properties of important natural and synthetic 2H-pyran-2-ones in organic synthesis were documented. 8,9 One of the earliest works describing the synthesis of the pyranothiazole ring from 3,5-dibromopyran-4-one and a thioamide was published in 1948.…”

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AbstractSyntheses of novel tetra-and penta-cyclic benzopyran and pyridopyran derivatives, via direct intramolecular arylation of 2-iodophenoxymethylhetarenes and 3-(2-bromo-pyridin-3-yloxymethyl)-benzo [4,5]

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