Chemistry, antioxidant and antimicrobial investigations on essential oil and oleoresins of Zingiber officinale

Singh, Gurdip; Kapoor, Inder Pal Singh; Singh, Pratibha; Heluani, Carola S. de; Lampasona, Marina P. de; Catalán, César A.N.

doi:10.1016/j.fct.2008.07.017

Cited by 357 publications

(260 citation statements)

References 27 publications

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“…The antifungal activities of the compounds were also studied by agar diffusion assay according to Singh et al (2008). The antifungal activities of the synthesized compounds were studied against various fungi Fusarim sp Gt-1019, Aspergillus flavus, Aspergillus oryzae, A.ochraceus, A. niger and Penicillium sp.…”

Section: Antifungal Activitymentioning

confidence: 99%

Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds

2011

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Dehydrozingerone, structural half analogue of curcumin, is a phenolic compound isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone and several of its derivatives such as glucopyranosides and its tetra acetate derivative and 4-O-acetyl and methyl derivatives of dehydrozingerone were synthesized in the present study. Dehydrozingerone, synthesised with improved yield was used for the synthesis of Dehydrozingerone 4-O-β-Dglucopyranoside (first time report) by modified KoenigsKnorr-Zemplén method. Structures of all the compounds have been established using spectroscopic methods. These compounds were tested for radical scavenging activity by DPPH and FRAP method as well as for antibacterial and antifungal activities. The parent molecule exhibited better scavenging activity as compared to its derivatives indicating the significance of free phenolic hydroxyl group. Also, Dehydrozingerone and its derivatives exhibited antibacterial as well as antifungal activity due to the conjugation system present, which includes α,β-unsaturated carbonyl (C = O) group. This study gave an insight into structural requirements for dehydrozingerone activity.

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Section: Antifungal Activitymentioning

confidence: 99%

Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds

2011

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“…[7] The antioxidative and free radical scavenging properties of the ginger extracts have been well established. [12,13] On the other hand, comparative studies of oleoresin and essential oil performed concomitantly, under the same conditions, have not yet been reported. It is well recognized that ginger's essential oil is much more lipophilic than the oleoresin.…”

Section: Essential Oil and Oleoresin Of Ginger 1305mentioning

confidence: 99%

“…Others, by studying this same plant reached similar results, also demonstrating that scavenging activity is a concentration dependent effect. [12,13] For concentrations of gallic acid and quercetin ranging from 0.0005 to 0.0025 mg/ml, the scavenging activity obtained evolved from 23.10 ± 0.91% to 91.49 ± 0.41% and from 13.07 ± 0.55% to 62.99 ± 0.93%, respectively. For ascorbic acid with concentrations ranging from 0.002 to 0.009 mg/ml, the scavenging activity evolved from 24.36 ± 1.14% to 94.51 ± 1.16%.…”

Section: Comparative Study Of the Antioxidant Activitymentioning

confidence: 99%

Antioxidant Activity of the Essential Oil and Oleoresin ofZingiber OfficinaleRoscoe as Affected by Chemical Environment

Bellik

Benabdesselam

Ayad

et al. 2013

International Journal of Food Properties

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Three different biochemical test systems were chosen based on their solubility to study the antioxidant activity of ginger extracts. Reducing power and DPPH . scavenging activity tests were considered to produce hydrophilic environments and the H 2 O 2 test was considered as creating a lipophilic environment. The average yields were 10.23 ± 1.02% and 0.48 ± 0.19% for oleoresin and essential oil, respectively. The content of total phenols was 67.6 ± 1.08 mg GAE/g of dry extract. In terms of EC 50 , in hydrophilic environment standards, it showed the highest effects compared to ginger extracts, with oleoresin presenting more activity than essential oil. In contrast, except for quercetin, essential oil showed the best scavenging activity in inhibiting H 2 O 2 compared to all other antioxidants. The present work demonstrated that, when using reducing power, DPPH· free radical scavenging and H 2 O 2 scavenging assays, the same ginger extracts exhibit different antioxidant activities, which were affected not only by the extract itself but also by the chemical environment (hydrophilic/lipophilic).

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“…The essential oil was extracted from fresh flowers of M. champaka by hydrodistillation using clevenger apparatus according to the modified method (Singh et al, 2008).…”

Section: Extraction Of Essential Oilmentioning

confidence: 99%

Evaluation of Antibacterial and Antioxidant activities of Essential oil from Michelia champaka

Batchu¹,

Mandava²,

Bhargav³

et al. 2017

J App Pharma Sci

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Antibiotic resistance has been called one of the world's most pressing public health problems. Irrational use of antibiotics promotes development of resistance against bacteria. The antimicrobial properties of medicinal plants are being increasingly reported from different parts of the world as they found to have lesser side effects and devoid of drug resistance. In an effort to expand the spectrum of antibacterial agents from natural sources the present study aimed to evaluate antibacterial and antioxidant activity of essential oil from the flowers of Michelia champaka (M. champaka). Essential oil was extracted from flowers of M. champaka by hydro distillation method using Clevenger's apparatus and screened for its antibacterial activity against gram positive (Micrococcus luteus, Streptococcus mutans) and gram negative (Escherichia coli, Salmonella typhi) strains. The minimum Inhibitory Concentration (MIC) of oil was determined using an agar diffusion method. Nevertheless the peroxide antioxidant assay was also performed. It was observed that essential oil has shown remarkable antibacterial activity against Streptococcus mutans (the causative agent for dental caries) with a zone of inhibition of 30 mm. A zone of inhibition was compared with standard antibiotic gentamicin. The MIC was reported as 25 mg/ml. The % inhibition of peroxide free radical was found to be 63.7% at 200mg/ml concentration. The antibacterial and antioxidant activity of M. champaka essential oil (MCEO) was due to various phytoconstituents. Hence MCEO can be used as an antibacterial source and phytoconstituents responsible for this activity can be explored and utilized in discovery of leads in the area of pharmacy research.

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Chemistry, antioxidant and antimicrobial investigations on essential oil and oleoresins of Zingiber officinale

Cited by 357 publications

References 27 publications

Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds

Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds

Antioxidant Activity of the Essential Oil and Oleoresin ofZingiber OfficinaleRoscoe as Affected by Chemical Environment

Evaluation of Antibacterial and Antioxidant activities of Essential oil from Michelia champaka

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