Chemometric-assisted QuEChERS extraction method for the residual analysis of thiacloprid, spirotetramat and spirotetramat’s four metabolites in pepper: Application of their dissipation patterns

Li, Shasha; Liu, Xingang; Dong, Fengshou; Xu, Jun; Xu, Hanqing; Hu, Mingfeng; Zheng, Yongquan

doi:10.1016/j.foodchem.2015.07.122

Cited by 47 publications

(34 citation statements)

References 30 publications

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“…A few studies have focused on some of the metabolites of BYI08330, particularly B‐enol, which has been reported in grapes (Mohapatra, Kumar, & Prakash, ), okra, brinjal leaves, green chillies, red chillies (Singh, Mandal, Sahoo, Bhardwaj, & Battu, ), apples (Han et al, ), mangoes and cabbages (Mohapatra, Deepa, & Jagadish, ). Recent publications discussing BYI08330 and its four metabolites in different matrices include various food contexts, such as pepper (S. S. Li, Liu, et al, ), cabbages, tomatoes, potatoes, apples, peaches and cucumbers (Zhu et al, ). Current analytical methods for the determination of spirotetramat and its metabolites are high‐performance liquid chromatography (HPLC) (Vemuri et al, ; Chahil et al, ; Singh et al, ; Mohapatra, Deepa, & Jagadish, ; Pandiselvi et al, ), ultra high‐performance chromatography coupled with tandem mass spectrometry (UPLC‐MS/MS) (S. S. Li, Liu, et al, ; Zhu et al, ), liquid chromatography with tandem mass spectrometry (LC‐MS/MS) (Chen et al, ) and gas chromatography mass spectrometry (GC/MS) (Mohapatra et al, ).…”

Section: Introductionmentioning

confidence: 99%

“…Recent publications discussing BYI08330 and its four metabolites in different matrices include various food contexts, such as pepper (S. S. Li, Liu, et al, ), cabbages, tomatoes, potatoes, apples, peaches and cucumbers (Zhu et al, ). Current analytical methods for the determination of spirotetramat and its metabolites are high‐performance liquid chromatography (HPLC) (Vemuri et al, ; Chahil et al, ; Singh et al, ; Mohapatra, Deepa, & Jagadish, ; Pandiselvi et al, ), ultra high‐performance chromatography coupled with tandem mass spectrometry (UPLC‐MS/MS) (S. S. Li, Liu, et al, ; Zhu et al, ), liquid chromatography with tandem mass spectrometry (LC‐MS/MS) (Chen et al, ) and gas chromatography mass spectrometry (GC/MS) (Mohapatra et al, ). To the best of our knowledge, there has been only one study focused on the dynamics of spirotetramat and its four metabolites in citrus marmalade during home processing by UPLC‐MS/MS (Liu et al, ).…”

Section: Introductionmentioning

confidence: 99%

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Dissipation, residues and risk assessment of spirotetramat and its four metabolites in citrus and soil under field conditions by LC‐MS/MS

Zhang

Chen

Wang

et al. 2017

Biomedical Chromatography

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A modified Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) method for the simultaneous determination of spirotetramat and its four metabolite residues in citrus, peel, pulp and soil was developed and validated by liquid chromatography with tandem mass spectrometry (LC-MS/MS). The samples were extracted with acetonitrile (1%, glacial acetic acid, v/v) and purified using primary secondary amine and octadecylsilane. The limit of detection was 0.01-0.13 mg/kg, whereas that of quantification was 0.02-0.40 mg/kg for spirotetramat and its metabolites. The average recoveries of spirotetramat, spirotetramat-enol, spirotetramat-mono-hydroxy, spirotetramat-enol-glucoside and spirotetramat-ketohydroxy in all matrices were 73.33-107.91%, 75.93-114.85%, 76.44-100.78%, 71.46-103.19% and 73.08-105.27%, respectively, with relative standard deviations < 12.32%. The dissipation dynamics of spirotetramat in citrus and soil followed first-order kinetics, with half-lives of 2.3-8.5 days in the three sampling locations. The terminal residues of spirotetramat in four matrices at the three locations were measured below the 1.0 mg/kg maximum residue limit set by China, and residues were found to be concentrated on the peel. The risk assessment of citrus was evaluated using risk quotients. The risk quotient values were found to be significantly <1, suggesting that the risk to human health was negligible when using the recommended doses of spirotetramat in citrus. These results could provide guidance for the safe and proper application of spirotetramat in citrus in China.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dissipation, residues and risk assessment of spirotetramat and its four metabolites in citrus and soil under field conditions by LC‐MS/MS

Zhang

Chen

Wang

et al. 2017

Biomedical Chromatography

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“…The QuEChERS poses the obvious advantages such as simple apparatus requirement, low consumption of toxic solvents, and high sample throughput . To date, the QuEChERS procedure followed by HPLC–MS/MS detection, which combines both the advantages of QuEChERS and HPLC–MS/MS, has become a popular and powerful protocol for multiresidue analysis of pesticides in different matrices .…”

Section: Introductionmentioning

confidence: 99%

Simultaneous determination of pyrifluquinazon and its main metabolite in fruits and vegetables by using QuEChERS–HPLC–MS/MS

You

Sui

et al. 2016

J of Separation Science

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A rapid, reliable, and sensitive method is reported for the simultaneous analysis of pyrifluquinazon and its main metabolite NNI-0101-1H in fruits (strawberry and cherry) and vegetables (cucumber and tomato) using high-performance liquid chromatography coupled with tandem mass spectrometry. A modified, quick, easy, cheap, effective, rugged, and safe procedure was used for the sample pre-preparation. The target analytes were extracted with acetonitrile and then cleaned up using dispersive solid-phase extraction procedure with primary secondary amine. Sample analysis was performed using electrospray ionization in positive mode. Good linearities with the correlation coefficients higher than 0.9991 were obtained in the range of 1-1000 μg/L under the optimized conditions. The average recoveries of the pyrifluquinazon and NNI-0101-1H were in the range of 71.4-106.0% with the relative standard deviations 1.8-11.8% in all matrices at three spiked levels (10, 100, and 1000 μg/kg). The limit of quantification 10 μg/kg was set as the lowest spiked level. The developed method is reliable and effective for the routine monitoring of pyrifluquinazon and its metabolite NNI-0101-1H in fruits and vegetables to ensure food safety.

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“…BYI08330-enol (B-enol), BYI08330keto-hydroxy (B-keto), BYI08330-mono-hydroxy (B-mono), and BYI08330-enol-glucoside (B-glu) are the major metabolites of spirotetramat. Some studies showed that maternal toxicity was observed at P40 mg/kg bw/day for spirotetramat; further research indicated that male reproductive toxicity is likely caused by the metabolite B-enol in rats 2,15 . Besides, for enforcement and risk assessment purposes in primary crops, spirotetramat, B-enol, B-keto, B-mono, and B-glu are contained in the definition.…”

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confidence: 99%

Simultaneous determination of spirodiclofen, spiromesifen, and spirotetramat and their relevant metabolites in edible fungi using ultra-performance liquid chromatography/tandem mass spectrometry

Tian

Qiao

Wang

et al. 2021

Sci Rep

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A fast, sensitive, and reliable analytical method was developed and validated for simultaneous identification and quantification of spirodiclofen, spiromesifen, and spirotetramat and their relevant metabolites in edible fungi by ultra-performance liquid chromatography/tandem mass spectrometry (UHPLC–MS/MS). First, sample extraction was done with acetonitrile containing 1% formic acid followed by phase separation with the addition of MgSO4:NaOAc. Then, the supernatant was purified by primary secondary amine (PSA), octadecylsilane (C18), and graphitized carbon black (GCB). The linearities of the calibrations for all analytes were excellent (R2 ≥ 0.9953). Acceptable recoveries (74.5–106.4%) for all analytes were obtained with good intra- and inter- relative standard deviations of less than 14.5%. The limit of quantification (LOQs) for all analytes was 10 μg kg−1. For accurate quantification, matrix-matched calibration curve was applied to normalize the matrix effect. The results indicated that the method was suitable for detecting the three acaricides and their relevant metabolites in edible fungi.

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Chemometric-assisted QuEChERS extraction method for the residual analysis of thiacloprid, spirotetramat and spirotetramat’s four metabolites in pepper: Application of their dissipation patterns

Cited by 47 publications

References 30 publications

Dissipation, residues and risk assessment of spirotetramat and its four metabolites in citrus and soil under field conditions by LC‐MS/MS

Dissipation, residues and risk assessment of spirotetramat and its four metabolites in citrus and soil under field conditions by LC‐MS/MS

Simultaneous determination of pyrifluquinazon and its main metabolite in fruits and vegetables by using QuEChERS–HPLC–MS/MS

Simultaneous determination of spirodiclofen, spiromesifen, and spirotetramat and their relevant metabolites in edible fungi using ultra-performance liquid chromatography/tandem mass spectrometry

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