Chemometrics and the identification of counterfeit medicines—A review

Krakowska, B.; Custers, D.; Deconinck, Éric; Daszykowski, M.

doi:10.1016/j.jpba.2016.04.016

Cited by 39 publications

(26 citation statements)

References 69 publications

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“…Modern literature on the use of machine learning methods in chemical analysis (chemometrics) is, in general, quite extensive and diverse. In recent years, a large number of reviews have been published on individual methods and analyzed objects [123][124][125][126][127]. However, the number of studies using chemometric methods, against the background of the total number of analytical works, is still extremely small.…”

Section: Spectroscopic Data Processing Using Chemometric Methods For mentioning

confidence: 99%

Low-Input Crops as Lignocellulosic Feedstock for Second-Generation Biorefineries and the Potential of Chemometrics in Biomass Quality Control

et al. 2019

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Lignocellulose feedstock (LCF) provides a sustainable source of components to produce bioenergy, biofuel, and novel biomaterials. Besides hard and soft wood, so-called low-input plants such as Miscanthus are interesting crops to be investigated as potential feedstock for the second generation biorefinery. The status quo regarding the availability and composition of different plants, including grasses and fast-growing trees (i.e., Miscanthus, Paulownia), is reviewed here. The second focus of this review is the potential of multivariate data processing to be used for biomass analysis and quality control. Experimental data obtained by spectroscopic methods, such as nuclear magnetic resonance (NMR) and Fourier-transform infrared spectroscopy (FTIR), can be processed using computational techniques to characterize the 3D structure and energetic properties of the feedstock building blocks, including complex linkages. Here, we provide a brief summary of recently reported experimental data for structural analysis of LCF biomasses, and give our perspectives on the role of chemometrics in understanding and elucidating on LCF composition and lignin 3D structure.

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Section: Spectroscopic Data Processing Using Chemometric Methods For mentioning

confidence: 99%

Low-Input Crops as Lignocellulosic Feedstock for Second-Generation Biorefineries and the Potential of Chemometrics in Biomass Quality Control

et al. 2019

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“…The steps of analytical procedures which involved FTIR spectroscopy and chemometrics techniques in meat authentication can be briefly described as (a) definition of authentication problems, (b) sampling process by taking authentic and adulterated meat products, (c) application of FTIR spectrophotometer to measure evaluated samples, (d) evaluation of FTIR spectral data, (e) selection of suitable chemometrics techniques, (f) pre-processing FTIR spectral data, if necessary, (g) choosing training and test sample sets, (h) optimization of models, either in training, validation or test samples, (i) selection of variables (absorbance values at selected wavenumbers), validation of developed model using selected variables, and (j) drawing of conclusion )[37].…”

Section: Methodsmentioning

confidence: 99%

Application of FTIR spectroscopy and chemometrics for authentication of meat and meat products: a review

Rohman

2019

J Adv Vet Anim Res

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Meat-based food such as meatball and sausages are important sources of protein needed for the human body. Due to different prices, some unethical producers try to adulterate high-price meat such as beef with lower priced meat like pork and rat meat to gain economical profits, therefore, reliable and fast analytical techniques should be developed, validated, and applied for meat traceability and authenticity. Some instrumental techniques have been applied for the detection of meat adulteration, mainly relied on DNA and protein using polymerase chain reaction and chromatographic methods, respectively. But, this method is time-consuming, needs a sophisticated instrument, involves complex sample preparation which make the method is not suitable for routine analysis. As a consequence, a simpler method based on spectroscopic principles should be continuously developed. Food samples are sometimes complex which resulted in complex chemical responses. Fortunately, a statistical method called with chemometrics could solve the problems related to complex chemical data. This mini-review highlights the application of Fourier-transform infrared spectroscopy coupled with numerous chemometrics techniques for authenticity and traceability of meat and meat-based products.

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“…Les résultats obtenus attestent de la bonne qualité des médicaments à base de chlorhydrate de doxorubicine utilisés dans les structures sanitaires de la Côte d'Ivoire. Cette méthode contribuerait à assurer la conformité des lots de médicaments à base de chlorhydrate de doxorubicine avant l'administration aux malades et à détecter les contrefaçons qui pourraient circuler en milieux hospitaliers (Höllein et al, 2016 ;Krakowska et al, 2016). Elle pourrait concourir à l'instauration systématique de contrôle postdistribution de médicaments anticancéreux à base de chlorhydrate de doxorubicine de Côte d'Ivoire.…”

Section: Conditions Opératoiresunclassified

Validation d’une méthode de dosage CLHP de l’anticancéreux chlorhydrate de doxorubicine dans des poudres lyophilisées pour préparation injectable

Kpaibe¹,

Amin²,

Soumahoro³

et al. 2017

Int. J. Bio. Chem. Sci

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Chemometrics and the identification of counterfeit medicines—A review

Cited by 39 publications

References 69 publications

Low-Input Crops as Lignocellulosic Feedstock for Second-Generation Biorefineries and the Potential of Chemometrics in Biomass Quality Control

Low-Input Crops as Lignocellulosic Feedstock for Second-Generation Biorefineries and the Potential of Chemometrics in Biomass Quality Control

Application of FTIR spectroscopy and chemometrics for authentication of meat and meat products: a review

Validation d’une méthode de dosage CLHP de l’anticancéreux chlorhydrate de doxorubicine dans des poudres lyophilisées pour préparation injectable

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