Chemomodulatory effects of Ichnocarpus frutescens R. Br against 4-vinylcyclohexane induced ovarian cancer in swiss albino mice

A study to assess the health effects of an anticancer drug (cyclophosphamide) in zebrafish (Danio rerio): eco-toxicity of emerging contaminants

“…Reduced glutathione (GSH) is an index of antioxidant status in biological systems and it helps to remove the hydrogen peroxide and serves as a cofactor for glutathione transferase. 89 CP is actively metabolised by cytochrome P450 to aldehyde phosphamide, amide phosphor-amide mustard, acrolein and reactive oxygen species. 90 These metabolites bind covalently to cellular nucleophiles and with reduced glutathione.…”