Chemoprevention of prostate cancer: What can be recommended to patients?

Colli, Janet; Amling, Christopher L.

doi:10.1007/s11934-009-0029-4

Cited by 26 publications

(11 citation statements)

References 45 publications

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“…Garlic and onion consumption was also associated with reduced risk of esophageal and stomach cancers, with greater risk reductions seen for higher levels of consumption [29]. Similarly, in another study, the consumption of allium vegetables, especially garlic and onions, was linked to a reduced risk of stomach cancer [30], an approximately 30-50 percent reduction in prostate cancer risk [31,32], pancreatic cancer [33] and other distinct cancer types [34]. Moreover, breast cancer risk was reduced in women consuming greater amounts of fiber garlic, and onions [35].…”

Section: Garlic and Onion (Allium Sativum L And Allium Cepa L)mentioning

confidence: 94%

Cancer Treatment by Greco-Arab and Islamic Herbal Medicine

Zaid¹,

Rayan²,

Саид³

et al. 2010

TONUTRAJ

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Islamic medicine, Arabic medicine, Arab-Islamic medicine, or Greco-Arab and Islamic medicine refers to medicine developed in the Golden Age of the Arab-Islamic civilization, which extended from Spain in the west to Central Asia and India in the east. In temporal terms it covered a period of roughly nine centuries, from the middle of the seventh to the end of the fifteenth century. Medicine was a central part of this medieval civilization. Famous Arab and Muslim physicians, e.g., Rhazes, Avicenna, Al Zahrawi, Ibn al Nafis studied and developed treatments regimes for cancer as well as most known diseases at that time. They described most types of cancers which were known at that time and suggested several therapies. This review is an eye-bird view on the ancient Arab-Greco and Islamic cancer diagnosis, herbal treatment and nowadays herbal treatment research.

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Section: Garlic and Onion (Allium Sativum L And Allium Cepa L)mentioning

confidence: 94%

Cancer Treatment by Greco-Arab and Islamic Herbal Medicine

Zaid¹,

Rayan²,

Саид³

et al. 2010

TONUTRAJ

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“…Several National Cancer Institute (NCI) initiatives continue to underscore the importance of including fruits and vegetables in the daily diet as a cancer chemopreventive measure (5,8 – 10) . Fruits and vegetables contain phytochemicals (carotenoids, polyphenolics, anthocyanins, alkaloids, N and S compounds) that have been shown to target multiple neoplastic stages to reduce overall cancer risk (11) .…”

mentioning

confidence: 99%

Benefits of whole ginger extract in prostate cancer

et al. 2011

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It is appreciated far and wide that increased and regular consumption of fruits and vegetables is linked with noteworthy anticancer benefits. Extensively consumed as a spice in foods and beverages worldwide, ginger (Zingiber officinale Roscoe) is an excellent source of several bioactive phenolics, including non-volatile pungent compounds such as gingerols, paradols, shogaols and gingerones. Ginger has been known to display anti-inflammatory, antioxidant and antiproliferative activities, indicating its promising role as a chemopreventive agent. Here, we show that whole ginger extract (GE) exerts significant growth-inhibitory and death-inductory effects in a spectrum of prostate cancer cells. Comprehensive studies have confirmed that GE perturbed cell-cycle progression, impaired reproductive capacity, modulated cell-cycle and apoptosis regulatory molecules and induced a caspase-driven, mitochondrially mediated apoptosis in human prostate cancer cells. Remarkably, daily oral feeding of 100 mg/kg body weight of GE inhibited growth and progression of PC-3 xenografts by approximately 56 % in nude mice, as shown by measurements of tumour volume. Tumour tissue from GE-treated mice showed reduced proliferation index and widespread apoptosis compared with controls, as determined by immunoblotting and immunohistochemical methods. Most importantly, GE did not exert any detectable toxicity in normal, rapidly dividing tissues such as gut and bone marrow. To the best of our knowledge, this is the first report to demonstrate the in vitro and in vivo anticancer activity of whole GE for the management of prostate cancer.

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“…The risk of breast cancer was also found to be reduced in women consuming greater amounts of fiber garlic and onions [31], as well as that of esophageal and stomach cancers [121]. Similar findings were noted with reference to the risk of prostate cancer [122, 123], pancreatic cancer [33], and other known cancer types [124]. The amount of garlic consumed in the above studies varied from 2 to 20 g daily (The World Health Organization (WHO) guidelines for general health promotion for adults recommend a daily dose of 2 to 5 g of fresh garlic).…”

Section: Cancer Prevention and Treatment In Greco-arab And Islamicmentioning

confidence: 62%

Greco-Arab and Islamic Herbal-Derived Anticancer Modalities: From Tradition to Molecular Mechanisms

Zaid

Silbermann

Ben‐Arye

et al. 2012

Evidence-Based Complementary and Alternative Medicine

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The incidence of cancer is increasing in the developed countries and even more so in developing countries parallel to the increase in life expectancy. In recent years, clinicians and researchers advocate the need to include supportive and palliative care since the establishment of the diagnosis and throughout the duration of treatment, with the goal of improving patients' quality of life. This patient-centered approach in supportive care is also shared by various traditional and complementary medicine approaches. Traditional Arab-Islamic medicine offers a variety of therapeutic modalities that include herbal, nutritional, and spiritual approaches. Physicians and scholars, such as Avicenna (980–1037), Rhazes (965–915), Al Zahrawi (936–1013), and Ibn al Nafis (1218–1288) referred to cancer etiology in various medicinal texts and suggested both preventive and therapeutic remedies to alleviate suffering. This review presents research data related to the anticancer activities of herbs used in Arab-Islamic medicine and allude to their potential role in improving the quality of life of cancer patients.

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Chemoprevention of prostate cancer: What can be recommended to patients?

Cited by 26 publications

References 45 publications

Cancer Treatment by Greco-Arab and Islamic Herbal Medicine

Cancer Treatment by Greco-Arab and Islamic Herbal Medicine

Benefits of whole ginger extract in prostate cancer

Greco-Arab and Islamic Herbal-Derived Anticancer Modalities: From Tradition to Molecular Mechanisms

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